Salazar DE - Search Results

1

Correlation of inhibition of platelet aggregation with cardiovascular and bleeding outcomes in acute coronary syndromes.

Wada R, Rohatagi S, Small D, Winters KJ, Salazar DE. Wada R, et al. Among authors: salazar de. J Clin Pharmacol. 2010 Aug;50(8):904-13. doi: 10.1177/0091270009353606. Epub 2010 Feb 10. J Clin Pharmacol. 2010. PMID: 20147617

2

Predictive population pharmacokinetic/pharmacodynamic model for a novel COX-2 inhibitor.

Rohatagi S, Kastrissios H, Gao Y, Zhang N, Xu J, Moberly J, Wada R, Yoshihara K, Takahashi M, Truitt K, Salazar D. Rohatagi S, et al. J Clin Pharmacol. 2007 Mar;47(3):358-70. doi: 10.1177/0091270006296152. J Clin Pharmacol. 2007. PMID: 17322148

3

Pharmacokinetics of amlodipine and olmesartan after administration of amlodipine besylate and olmesartan medoxomil in separate dosage forms and as a fixed-dose combination.

Rohatagi S, Lee J, Shenouda M, Haworth S, Bathala MS, Allison M, Rubets I, Heyrman R, Noveck R, Salazar DE. Rohatagi S, et al. Among authors: salazar de. J Clin Pharmacol. 2008 Nov;48(11):1309-22. doi: 10.1177/0091270008322176. J Clin Pharmacol. 2008. PMID: 18974285

4

Cytochrome P450 3A inhibition by ketoconazole affects prasugrel and clopidogrel pharmacokinetics and pharmacodynamics differently.

Farid NA, Payne CD, Small DS, Winters KJ, Ernest CS 2nd, Brandt JT, Darstein C, Jakubowski JA, Salazar DE. Farid NA, et al. Among authors: salazar de. Clin Pharmacol Ther. 2007 May;81(5):735-41. doi: 10.1038/sj.clpt.6100139. Epub 2007 Mar 14. Clin Pharmacol Ther. 2007. PMID: 17361128 Clinical Trial.

5

The use of modeling and simulation to guide clinical development of olmesartan medoxomil in pediatric subjects.

Salazar DE, Song SH, Shi J, Rohatagi S, Heyrman R, Wada DR, Carrothers TJ. Salazar DE, et al. Clin Pharmacol Ther. 2012 Feb;91(2):250-6. doi: 10.1038/clpt.2011.220. Epub 2011 Dec 28. Clin Pharmacol Ther. 2012. PMID: 22205195

6

Evaluation of population pharmacokinetics and exposure-response relationship with coadministration of amlodipine besylate and olmesartan medoxomil.

Rohatagi S, Carrothers TJ, Kshirsagar S, Khariton T, Lee J, Salazar D. Rohatagi S, et al. J Clin Pharmacol. 2008 Jul;48(7):823-36. doi: 10.1177/0091270008317847. Epub 2008 May 19. J Clin Pharmacol. 2008. PMID: 18490496 Clinical Trial.

7

Population pharmacokinetic analyses to evaluate the influence of intrinsic and extrinsic factors on exposure of prasugrel active metabolite in TRITON-TIMI 38.

Wrishko RE, Ernest CS 2nd, Small DS, Li YG, Weerakkody GJ, Riesmeyer JR, Macias WL, Rohatagi S, Salazar DE, Antman EM, Wiviott SD, Braunwald E, Ni L. Wrishko RE, et al. Among authors: salazar de. J Clin Pharmacol. 2009 Aug;49(8):984-98. doi: 10.1177/0091270009337942. Epub 2009 Jun 22. J Clin Pharmacol. 2009. PMID: 19546250

8

Quantitative structure-property relationships modeling to predict in vitro and in vivo binding of drugs to the bile sequestrant, colesevelam (Welchol).

Walker JR, Brown K, Rohatagi S, Bathala MS, Xu C, Wickremasingha PK, Salazar DE, Mager DE. Walker JR, et al. Among authors: salazar de. J Clin Pharmacol. 2009 Oct;49(10):1185-95. doi: 10.1177/0091270009340783. J Clin Pharmacol. 2009. PMID: 19783712

9

The pharmacokinetics and pharmacodynamics of prasugrel in healthy Chinese, Japanese, and Korean subjects compared with healthy Caucasian subjects.

Small DS, Kothare P, Yuen E, Lachno DR, Li YG, Winters KJ, Farid NA, Ni L, Jakubowski JA, Salazar DE, Thieu VT, Payne CD. Small DS, et al. Among authors: salazar de. Eur J Clin Pharmacol. 2010 Feb;66(2):127-35. doi: 10.1007/s00228-009-0737-1. Epub 2009 Nov 4. Eur J Clin Pharmacol. 2010. PMID: 19888568 Clinical Trial.

10

Effect of intrinsic and extrinsic factors on the clinical pharmacokinetics and pharmacodynamics of prasugrel.

Small DS, Farid NA, Payne CD, Konkoy CS, Jakubowski JA, Winters KJ, Salazar DE. Small DS, et al. Among authors: salazar de. Clin Pharmacokinet. 2010 Dec;49(12):777-98. doi: 10.2165/11537820-000000000-00000. Clin Pharmacokinet. 2010. PMID: 21053990 Review.

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