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Direct angiotensin II type 2 receptor stimulation acts anti-inflammatory through epoxyeicosatrienoic acid and inhibition of nuclear factor kappaB.
Rompe F, Artuc M, Hallberg A, Alterman M, Ströder K, Thöne-Reineke C, Reichenbach A, Schacherl J, Dahlöf B, Bader M, Alenina N, Schwaninger M, Zuberbier T, Funke-Kaiser H, Schmidt C, Schunck WH, Unger T, Steckelings UM. Rompe F, et al. Hypertension. 2010 Apr;55(4):924-31. doi: 10.1161/HYPERTENSIONAHA.109.147843. Epub 2010 Feb 15. Hypertension. 2010. PMID: 20157051
Are angiotensin receptor blockers neuroprotective?
Thöne-Reineke C, Zimmermann M, Neumann C, Krikov M, Li J, Gerova N, Unger T. Thöne-Reineke C, et al. Curr Hypertens Rep. 2004 Aug;6(4):257-66. doi: 10.1007/s11906-004-0019-3. Curr Hypertens Rep. 2004. PMID: 15257859 Review.
The beta-lactam antibiotic, ceftriaxone, dramatically improves survival, increases glutamate uptake and induces neurotrophins in stroke.
Thöne-Reineke C, Neumann C, Namsolleck P, Schmerbach K, Krikov M, Schefe JH, Lucht K, Hörtnagl H, Godes M, Müller S, Rumschüssel K, Funke-Kaiser H, Villringer A, Steckelings UM, Unger T. Thöne-Reineke C, et al. J Hypertens. 2008 Dec;26(12):2426-35. doi: 10.1097/HJH.0b013e328313e403. J Hypertens. 2008. PMID: 19008722
The promyelocytic leukemia zinc finger (PLZF) protein exerts neuroprotective effects in neuronal cells and is dysregulated in experimental stroke.
Seidel K, Kirsch S, Lucht K, Zaade D, Reinemund J, Schmitz J, Klare S, Li Y, Schefe JH, Schmerbach K, Goldin-Lang P, Zollmann FS, Thöne-Reineke C, Unger T, Funke-Kaiser H. Seidel K, et al. Brain Pathol. 2011 Jan;21(1):31-43. doi: 10.1111/j.1750-3639.2010.00427.x. Brain Pathol. 2011. PMID: 20731660 Free PMC article.
90 results