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Defibrotide for the treatment of severe hepatic veno-occlusive disease and multiorgan failure after stem cell transplantation: a multicenter, randomized, dose-finding trial.
Richardson PG, Soiffer RJ, Antin JH, Uno H, Jin Z, Kurtzberg J, Martin PL, Steinbach G, Murray KF, Vogelsang GB, Chen AR, Krishnan A, Kernan NA, Avigan DE, Spitzer TR, Shulman HM, Di Salvo DN, Revta C, Warren D, Momtaz P, Bradwin G, Wei LJ, Iacobelli M, McDonald GB, Guinan EC. Richardson PG, et al. Among authors: iacobelli m. Biol Blood Marrow Transplant. 2010 Jul;16(7):1005-17. doi: 10.1016/j.bbmt.2010.02.009. Epub 2010 Feb 16. Biol Blood Marrow Transplant. 2010. PMID: 20167278 Free PMC article. Clinical Trial.
Treatment of severe veno-occlusive disease with defibrotide: compassionate use results in response without significant toxicity in a high-risk population.
Richardson PG, Elias AD, Krishnan A, Wheeler C, Nath R, Hoppensteadt D, Kinchla NM, Neuberg D, Waller EK, Antin JH, Soiffer R, Vredenburgh J, Lill M, Woolfrey AE, Bearman SI, Iacobelli M, Fareed J, Guinan EC. Richardson PG, et al. Among authors: iacobelli m. Blood. 1998 Aug 1;92(3):737-44. Blood. 1998. PMID: 9680339 Free article. Review.
Hepatic veno-occlusive disease following stem cell transplantation: incidence, clinical course, and outcome.
Coppell JA, Richardson PG, Soiffer R, Martin PL, Kernan NA, Chen A, Guinan E, Vogelsang G, Krishnan A, Giralt S, Revta C, Carreau NA, Iacobelli M, Carreras E, Ruutu T, Barbui T, Antin JH, Niederwieser D. Coppell JA, et al. Among authors: iacobelli m. Biol Blood Marrow Transplant. 2010 Feb;16(2):157-68. doi: 10.1016/j.bbmt.2009.08.024. Epub 2009 Sep 18. Biol Blood Marrow Transplant. 2010. PMID: 19766729 Free PMC article. Review.
Melphalan, prednisone, thalidomide and defibrotide in relapsed/refractory multiple myeloma: results of a multicenter phase I/II trial.
Palumbo A, Larocca A, Genuardi M, Kotwica K, Gay F, Rossi D, Benevolo G, Magarotto V, Cavallo F, Bringhen S, Rus C, Masini L, Iacobelli M, Gaidano G, Mitsiades C, Anderson K, Boccadoro M, Richardson P; Italian Multiple Myeloma Network GIMEMA. Palumbo A, et al. Among authors: iacobelli m. Haematologica. 2010 Jul;95(7):1144-9. doi: 10.3324/haematol.2009.017913. Epub 2010 Jan 6. Haematologica. 2010. PMID: 20053869 Free PMC article. Clinical Trial.
Defibrotide blunts the prothrombotic effect of thalidomide on endothelial cells.
Echart CL, Somaini S, Distaso M, Palumbo A, Richardson PG, Fareed J, Iacobelli M. Echart CL, et al. Among authors: iacobelli m. Clin Appl Thromb Hemost. 2012 Jan-Feb;18(1):79-86. doi: 10.1177/1076029611412367. Epub 2011 Jul 6. Clin Appl Thromb Hemost. 2012. PMID: 21733935 Free article.
99 results