Sprick MR - Search Results

1

Oncogenic K-Ras turns death receptors into metastasis-promoting receptors in human and mouse colorectal cancer cells.

Hoogwater FJ, Nijkamp MW, Smakman N, Steller EJ, Emmink BL, Westendorp BF, Raats DA, Sprick MR, Schaefer U, Van Houdt WJ, De Bruijn MT, Schackmann RC, Derksen PW, Medema JP, Walczak H, Borel Rinkes IH, Kranenburg O. Hoogwater FJ, et al. Among authors: sprick mr. Gastroenterology. 2010 Jun;138(7):2357-67. doi: 10.1053/j.gastro.2010.02.046. Epub 2010 Feb 23. Gastroenterology. 2010. PMID: 20188103

2

The interplay between the Bcl-2 family and death receptor-mediated apoptosis.

Sprick MR, Walczak H. Sprick MR, et al. Biochim Biophys Acta. 2004 Mar 1;1644(2-3):125-32. doi: 10.1016/j.bbamcr.2003.11.002. Biochim Biophys Acta. 2004. PMID: 14996497 Free article. Review.

3

Cancer stem cells--old concepts, new insights.

Vermeulen L, Sprick MR, Kemper K, Stassi G, Medema JP. Vermeulen L, et al. Among authors: sprick mr. Cell Death Differ. 2008 Jun;15(6):947-58. doi: 10.1038/cdd.2008.20. Epub 2008 Feb 15. Cell Death Differ. 2008. PMID: 18259194 Review.

4

Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signalling complexes in a FADD-dependent manner but can not functionally substitute caspase-8.

Sprick MR, Rieser E, Stahl H, Grosse-Wilde A, Weigand MA, Walczak H. Sprick MR, et al. EMBO J. 2002 Sep 2;21(17):4520-30. doi: 10.1093/emboj/cdf441. EMBO J. 2002. PMID: 12198154 Free PMC article.

5

TRAIL-induced apoptosis and gene induction in HaCaT keratinocytes: differential contribution of TRAIL receptors 1 and 2.

Leverkus M, Sprick MR, Wachter T, Denk A, Bröcker EB, Walczak H, Neumann M. Leverkus M, et al. Among authors: sprick mr. J Invest Dermatol. 2003 Jul;121(1):149-55. doi: 10.1046/j.1523-1747.2003.12332.x. J Invest Dermatol. 2003. PMID: 12839575 Free article.

6

TRAIL/bortezomib cotreatment is potentially hepatotoxic but induces cancer-specific apoptosis within a therapeutic window.

Koschny R, Ganten TM, Sykora J, Haas TL, Sprick MR, Kolb A, Stremmel W, Walczak H. Koschny R, et al. Among authors: sprick mr. Hepatology. 2007 Mar;45(3):649-58. doi: 10.1002/hep.21555. Hepatology. 2007. PMID: 17326159

7

cFLIPL inhibits tumor necrosis factor-related apoptosis-inducing ligand-mediated NF-kappaB activation at the death-inducing signaling complex in human keratinocytes.

Wachter T, Sprick M, Hausmann D, Kerstan A, McPherson K, Stassi G, Bröcker EB, Walczak H, Leverkus M. Wachter T, et al. J Biol Chem. 2004 Dec 17;279(51):52824-34. doi: 10.1074/jbc.M409554200. Epub 2004 Sep 30. J Biol Chem. 2004. PMID: 15459191 Free article.

8

Martin Leverkus, 1965-2016.

Walczak H, Sprick MR. Walczak H, et al. Among authors: sprick mr. Cell Death Discov. 2017 Jan 23;3:16093. doi: 10.1038/cddiscovery.2016.93. eCollection 2017. Cell Death Discov. 2017. PMID: 28179992 Free PMC article. No abstract available.

9

FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2.

Sprick MR, Weigand MA, Rieser E, Rauch CT, Juo P, Blenis J, Krammer PH, Walczak H. Sprick MR, et al. Immunity. 2000 Jun;12(6):599-609. doi: 10.1016/s1074-7613(00)80211-3. Immunity. 2000. PMID: 10894160 Free article.

10

Biochemistry and function of the DISC.

Walczak H, Sprick MR. Walczak H, et al. Among authors: sprick mr. Trends Biochem Sci. 2001 Jul;26(7):452-3. doi: 10.1016/s0968-0004(01)01895-3. Trends Biochem Sci. 2001. PMID: 11440858 No abstract available.

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