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Loss of fibroblast HIF-1α accelerates tumorigenesis.
Kim JW, Evans C, Weidemann A, Takeda N, Lee YS, Stockmann C, Branco-Price C, Brandberg F, Leone G, Ostrowski MC, Johnson RS. Kim JW, et al. Cancer Res. 2012 Jul 1;72(13):3187-95. doi: 10.1158/0008-5472.CAN-12-0534. Epub 2012 May 3. Cancer Res. 2012. PMID: 22556263 Free PMC article.
You don't need a PHD to grow a tumor.
Kim JW, Johnson RS. Kim JW, et al. Dev Cell. 2009 Jun;16(6):781-2. doi: 10.1016/j.devcel.2009.06.001. Dev Cell. 2009. PMID: 19531349 Free article.
HIF isoforms in the skin differentially regulate systemic arterial pressure.
Cowburn AS, Takeda N, Boutin AT, Kim JW, Sterling JC, Nakasaki M, Southwood M, Goldrath AW, Jamora C, Nizet V, Chilvers ER, Johnson RS. Cowburn AS, et al. Among authors: kim jw. Proc Natl Acad Sci U S A. 2013 Oct 22;110(43):17570-5. doi: 10.1073/pnas.1306942110. Epub 2013 Oct 7. Proc Natl Acad Sci U S A. 2013. PMID: 24101470 Free PMC article.
HIF-1α-PDK1 axis-induced active glycolysis plays an essential role in macrophage migratory capacity.
Semba H, Takeda N, Isagawa T, Sugiura Y, Honda K, Wake M, Miyazawa H, Yamaguchi Y, Miura M, Jenkins DM, Choi H, Kim JW, Asagiri M, Cowburn AS, Abe H, Soma K, Koyama K, Katoh M, Sayama K, Goda N, Johnson RS, Manabe I, Nagai R, Komuro I. Semba H, et al. Among authors: kim jw. Nat Commun. 2016 May 18;7:11635. doi: 10.1038/ncomms11635. Nat Commun. 2016. PMID: 27189088 Free PMC article.
Macrophage hypoxia signaling regulates cardiac fibrosis via Oncostatin M.
Abe H, Takeda N, Isagawa T, Semba H, Nishimura S, Morioka MS, Nakagama Y, Sato T, Soma K, Koyama K, Wake M, Katoh M, Asagiri M, Neugent ML, Kim JW, Stockmann C, Yonezawa T, Inuzuka R, Hirota Y, Maemura K, Yamashita T, Otsu K, Manabe I, Nagai R, Komuro I. Abe H, et al. Among authors: kim jw. Nat Commun. 2019 Jun 27;10(1):2824. doi: 10.1038/s41467-019-10859-w. Nat Commun. 2019. PMID: 31249305 Free PMC article.
Targeting Hypoxia-Inducible Factor-1α/Pyruvate Dehydrogenase Kinase 1 Axis by Dichloroacetate Suppresses Bleomycin-induced Pulmonary Fibrosis.
Goodwin J, Choi H, Hsieh MH, Neugent ML, Ahn JM, Hayenga HN, Singh PK, Shackelford DB, Lee IK, Shulaev V, Dhar S, Takeda N, Kim JW. Goodwin J, et al. Among authors: kim jw. Am J Respir Cell Mol Biol. 2018 Feb;58(2):216-231. doi: 10.1165/rcmb.2016-0186OC. Am J Respir Cell Mol Biol. 2018. PMID: 28915065 Free PMC article.
The interplay between MYC and HIF in cancer.
Dang CV, Kim JW, Gao P, Yustein J. Dang CV, et al. Among authors: kim jw. Nat Rev Cancer. 2008 Jan;8(1):51-6. doi: 10.1038/nrc2274. Nat Rev Cancer. 2008. PMID: 18046334 Review.
9,003 results