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Page 1
Regulatory T cells are strong promoters of acute ischemic stroke in mice by inducing dysfunction of the cerebral microvasculature.
Kleinschnitz C, Kraft P, Dreykluft A, Hagedorn I, Göbel K, Schuhmann MK, Langhauser F, Helluy X, Schwarz T, Bittner S, Mayer CT, Brede M, Varallyay C, Pham M, Bendszus M, Jakob P, Magnus T, Meuth SG, Iwakura Y, Zernecke A, Sparwasser T, Nieswandt B, Stoll G, Wiendl H. Kleinschnitz C, et al. Among authors: dreykluft a. Blood. 2013 Jan 24;121(4):679-91. doi: 10.1182/blood-2012-04-426734. Epub 2012 Nov 15. Blood. 2013. PMID: 23160472 Free PMC article.
B7-H1 shapes T-cell-mediated brain endothelial cell dysfunction and regional encephalitogenicity in spontaneous CNS autoimmunity.
Klotz L, Kuzmanov I, Hucke S, Gross CC, Posevitz V, Dreykluft A, Schulte-Mecklenbeck A, Janoschka C, Lindner M, Herold M, Schwab N, Ludwig-Portugall I, Kurts C, Meuth SG, Kuhlmann T, Wiendl H. Klotz L, et al. Among authors: dreykluft a. Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):E6182-E6191. doi: 10.1073/pnas.1601350113. Epub 2016 Sep 26. Proc Natl Acad Sci U S A. 2016. PMID: 27671636 Free PMC article.
CD4(+) CD25(+) FoxP3(+) regulatory T cells suppress cytotoxicity of CD8(+) effector T cells: implications for their capacity to limit inflammatory central nervous system damage at the parenchymal level.
Göbel K, Bittner S, Melzer N, Pankratz S, Dreykluft A, Schuhmann MK, Meuth SG, Wiendl H. Göbel K, et al. Among authors: dreykluft a. J Neuroinflammation. 2012 Feb 28;9:41. doi: 10.1186/1742-2094-9-41. J Neuroinflammation. 2012. PMID: 22373353 Free PMC article.