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trans-4-[4-(Methoxyphenyl)cyclohexyl]-1-arylpiperazines: a new class of potent and selective 5-HT(1A) receptor ligands as conformationally constrained analogues of 4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]-1-arylpiperazines.
Perrone R, Berardi F, Colabufo NA, Leopoldo M, Lacivita E, Tortorella V, Leonardi A, Poggesi E, Testa R. Perrone R, et al. Among authors: colabufo na. J Med Chem. 2001 Dec 6;44(25):4431-42. doi: 10.1021/jm010866v. J Med Chem. 2001. PMID: 11728188
Synthesis and toxicopharmacological evaluation of m-hydroxymexiletine, the first metabolite of mexiletine more potent than the parent compound on voltage-gated sodium channels.
Catalano A, Desaphy JF, Lentini G, Carocci A, Di Mola A, Bruno C, Carbonara R, De Palma A, Budriesi R, Ghelardini C, Perrone MG, Colabufo NA, Conte Camerino D, Franchini C. Catalano A, et al. Among authors: colabufo na. J Med Chem. 2012 Feb 9;55(3):1418-22. doi: 10.1021/jm201197z. Epub 2012 Jan 31. J Med Chem. 2012. PMID: 22191686
Investigations on the 1-(2-biphenyl)piperazine motif: identification of new potent and selective ligands for the serotonin(7) (5-HT(7)) receptor with agonist or antagonist action in vitro or ex vivo.
Lacivita E, Patarnello D, Stroth N, Caroli A, Niso M, Contino M, De Giorgio P, Di Pilato P, Colabufo NA, Berardi F, Perrone R, Svenningsson P, Hedlund PB, Leopoldo M. Lacivita E, et al. Among authors: colabufo na. J Med Chem. 2012 Jul 26;55(14):6375-80. doi: 10.1021/jm3003679. Epub 2012 Jul 11. J Med Chem. 2012. PMID: 22738316
183 results