Crawford NT - Search Results

1

T-box 2 represses NDRG1 through an EGR1-dependent mechanism to drive the proliferation of breast cancer cells.

Redmond KL, Crawford NT, Farmer H, D'Costa ZC, O'Brien GJ, Buckley NE, Kennedy RD, Johnston PG, Harkin DP, Mullan PB. Redmond KL, et al. Among authors: crawford nt. Oncogene. 2010 Jun 3;29(22):3252-62. doi: 10.1038/onc.2010.84. Epub 2010 Mar 29. Oncogene. 2010. PMID: 20348948

2

Dynamical systems analysis of mitochondrial BAK activation kinetics predicts resistance to BH3 domains.

Grills C, Crawford N, Chacko A, Johnston PG, O'Rourke F, Fennell DA. Grills C, et al. PLoS One. 2008 Aug 22;3(8):e3038. doi: 10.1371/journal.pone.0003038. PLoS One. 2008. PMID: 18725943 Free PMC article.

3

Machine vision based stochastic analysis of cancer cell mitochondrial dysfunction induced by a BH3 domain.

Chacko AD, Crawford NT, Johnston PG, Fennell DA. Chacko AD, et al. Among authors: crawford nt. Apoptosis. 2008 Nov;13(11):1386-93. doi: 10.1007/s10495-008-0262-1. Apoptosis. 2008. PMID: 18814032

4

Procaspase 8 overexpression in non-small-cell lung cancer promotes apoptosis induced by FLIP silencing.

Wilson TR, Redmond KM, McLaughlin KM, Crawford N, Gately K, O'Byrne K, Le-Clorrenec C, Holohan C, Fennell DA, Johnston PG, Longley DB. Wilson TR, et al. Cell Death Differ. 2009 Oct;16(10):1352-61. doi: 10.1038/cdd.2009.76. Epub 2009 Jun 19. Cell Death Differ. 2009. PMID: 19543235

5

BRD7, a subunit of SWI/SNF complexes, binds directly to BRCA1 and regulates BRCA1-dependent transcription.

Harte MT, O'Brien GJ, Ryan NM, Gorski JJ, Savage KI, Crawford NT, Mullan PB, Harkin DP. Harte MT, et al. Among authors: crawford nt. Cancer Res. 2010 Mar 15;70(6):2538-47. doi: 10.1158/0008-5472.CAN-09-2089. Epub 2010 Mar 9. Cancer Res. 2010. PMID: 20215511

6

Platinum resistant cancer cells conserve sensitivity to BH3 domains and obatoclax induced mitochondrial apoptosis.

Crawford N, Chacko AD, Savage KI, McCoy F, Redmond K, Longley DB, Fennell DA. Crawford N, et al. Apoptosis. 2011 Mar;16(3):311-20. doi: 10.1007/s10495-010-0561-1. Apoptosis. 2011. PMID: 21107700

7

The DeltaNp63 proteins are key allies of BRCA1 in the prevention of basal-like breast cancer.

Buckley NE, Conlon SJ, Jirstrom K, Kay EW, Crawford NT, O'Grady A, Sheehan K, Mc Dade SS, Wang CW, McCance DJ, Johnston PG, Kennedy RD, Harkin DP, Mullan PB. Buckley NE, et al. Among authors: crawford nt. Cancer Res. 2011 Mar 1;71(5):1933-44. doi: 10.1158/0008-5472.CAN-10-2717. Cancer Res. 2011. PMID: 21363924

8

BRCA1 and GATA3 corepress FOXC1 to inhibit the pathogenesis of basal-like breast cancers.

Tkocz D, Crawford NT, Buckley NE, Berry FB, Kennedy RD, Gorski JJ, Harkin DP, Mullan PB. Tkocz D, et al. Among authors: crawford nt. Oncogene. 2012 Aug 9;31(32):3667-78. doi: 10.1038/onc.2011.531. Epub 2011 Nov 28. Oncogene. 2012. PMID: 22120723

9

BRCA1 is a key regulator of breast differentiation through activation of Notch signalling with implications for anti-endocrine treatment of breast cancers.

Buckley NE, Nic An tSaoir CB, Blayney JK, Oram LC, Crawford NT, D'Costa ZC, Quinn JE, Kennedy RD, Harkin DP, Mullan PB. Buckley NE, et al. Among authors: crawford nt. Nucleic Acids Res. 2013 Oct;41(18):8601-14. doi: 10.1093/nar/gkt626. Epub 2013 Jul 17. Nucleic Acids Res. 2013. PMID: 23863842 Free PMC article.

10

SAHA overcomes FLIP-mediated inhibition of SMAC mimetic-induced apoptosis in mesothelioma.

Crawford N, Stasik I, Holohan C, Majkut J, McGrath M, Johnston PG, Chessari G, Ward GA, Waugh DJ, Fennell DA, Longley DB. Crawford N, et al. Cell Death Dis. 2013 Jul 18;4(7):e733. doi: 10.1038/cddis.2013.258. Cell Death Dis. 2013. PMID: 23868066 Free PMC article.

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