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The GATA-3-dependent transcriptome and tumor microenvironment are regulated by eIF4E and XPO1 in T-cell lymphomas.
Kady N, Abdelrahman S, Rauf A, Burgess A, Weiss J, Gunasekara H, Ramseier NT, Maine IP, Zevallos-Morales A, Perez-Silos V, Wolfe A, Hristov A, Brown NA, Inamdar KV, Sverdlov M, Hu YS, Murga-Zamalloa C, Wang C, Wilcox RA. Kady N, et al. Among authors: hu ys. Blood. 2024 Dec 9:blood.2024025484. doi: 10.1182/blood.2024025484. Online ahead of print. Blood. 2024. PMID: 39652777
A potent and selective reaction hijacking inhibitor of Plasmodium falciparum tyrosine tRNA synthetase exhibits single dose oral efficacy in vivo.
Xie SC, Tai CW, Morton CJ, Ma L, Huang SC, Wittlin S, Du Y, Hu Y, Dogovski C, Salimimarand M, Griffin R, England D, de la Cruz E, Deni I, Yeo T, Burkhard AY, Striepen J, Schindler KA, Crespo B, Gamo FJ, Khandokar Y, Hutton CA, Rabie T, Birkholtz LM, Famodimu MT, Delves MJ, Bolsher J, Koolen KMJ, van der Laak R, Aguiar ACC, Pereira DB, Guido RVC, Creek DJ, Fidock DA, Dick LR, Brand SL, Gould AE, Langston S, Griffin MDW, Tilley L. Xie SC, et al. Among authors: hu y. PLoS Pathog. 2024 Dec 9;20(12):e1012429. doi: 10.1371/journal.ppat.1012429. Online ahead of print. PLoS Pathog. 2024. PMID: 39652589
Androgen receptor inhibition increases MHC Class I expression and improves immune response in prostate cancer.
Chesner LN, Polesso F, Graff JN, Hawley JE, Smith AK, Lundberg A, Das R, Shenoy T, Sjöström M, Zhao F, Hu YM, Linder S, Chen WS, Hawkins RM, Shrestha R, Zhu X, Foye A, Li H, Kim LM, Bhalla M, O'loughlin T, Kuzuoglu-Ozturk D, Hua JT, Badura ML, Wilkinson S, Trostel SY, Bergman AM, Ruggero D, Drake CG, Sowalsky AG, Fong L, Cooperberg MR, Zwart W, Guan X, Ashworth A, Xia Z, Quigley DA, Gilbert LA, Feng FY, Moran AE. Chesner LN, et al. Among authors: hu ym. Cancer Discov. 2024 Dec 5. doi: 10.1158/2159-8290.CD-24-0559. Online ahead of print. Cancer Discov. 2024. PMID: 39652470
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