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Genetic evidence that SOST inhibits WNT signaling in the limb.
Collette NM, Genetos DC, Murugesh D, Harland RM, Loots GG. Collette NM, et al. Among authors: genetos dc. Dev Biol. 2010 Jun 15;342(2):169-79. doi: 10.1016/j.ydbio.2010.03.021. Epub 2010 Mar 30. Dev Biol. 2010. PMID: 20359476 Free PMC article.
TGF-β regulates sclerostin expression via the ECR5 enhancer.
Loots GG, Keller H, Leupin O, Murugesh D, Collette NM, Genetos DC. Loots GG, et al. Among authors: genetos dc. Bone. 2012 Mar;50(3):663-9. doi: 10.1016/j.bone.2011.11.016. Epub 2011 Dec 2. Bone. 2012. PMID: 22155511 Free PMC article.
Targeted deletion of Sost distal enhancer increases bone formation and bone mass.
Collette NM, Genetos DC, Economides AN, Xie L, Shahnazari M, Yao W, Lane NE, Harland RM, Loots GG. Collette NM, et al. Among authors: genetos dc. Proc Natl Acad Sci U S A. 2012 Aug 28;109(35):14092-7. doi: 10.1073/pnas.1207188109. Epub 2012 Aug 10. Proc Natl Acad Sci U S A. 2012. PMID: 22886088 Free PMC article.
57 results