Colomer D - Search Results

1

Cell death targeting therapies in B lymphoid malignancies.

Saborit-Villarroya I, Roué G, López-Guerra M, Alonso R, Xargay-Torrent S, Rosich L, Colomer D. Saborit-Villarroya I, et al. Among authors: colomer d. Curr Drug Targets. 2010 Jul;11(7):769-80. doi: 10.2174/138945010791320863. Curr Drug Targets. 2010. PMID: 20370650 Review.

2

The proteasome inhibitor bortezomib induces apoptosis in mantle-cell lymphoma through generation of ROS and Noxa activation independent of p53 status.

Pérez-Galán P, Roué G, Villamor N, Montserrat E, Campo E, Colomer D. Pérez-Galán P, et al. Among authors: colomer d. Blood. 2006 Jan 1;107(1):257-64. doi: 10.1182/blood-2005-05-2091. Epub 2005 Sep 15. Blood. 2006. PMID: 16166592 Free article.

3

The BH3-mimetic GX15-070 synergizes with bortezomib in mantle cell lymphoma by enhancing Noxa-mediated activation of Bak.

Pérez-Galán P, Roué G, Villamor N, Campo E, Colomer D. Pérez-Galán P, et al. Among authors: colomer d. Blood. 2007 May 15;109(10):4441-9. doi: 10.1182/blood-2006-07-034173. Epub 2007 Jan 16. Blood. 2007. PMID: 17227835 Free article.

4

Selective inhibition of IkappaB kinase sensitizes mantle cell lymphoma B cells to TRAIL by decreasing cellular FLIP level.

Roué G, Pérez-Galán P, López-Guerra M, Villamor N, Campo E, Colomer D. Roué G, et al. Among authors: colomer d. J Immunol. 2007 Feb 1;178(3):1923-30. doi: 10.4049/jimmunol.178.3.1923. J Immunol. 2007. PMID: 17237443

5

Genetic and molecular pathogenesis of mantle cell lymphoma: perspectives for new targeted therapeutics.

Jares P, Colomer D, Campo E. Jares P, et al. Among authors: colomer d. Nat Rev Cancer. 2007 Oct;7(10):750-62. doi: 10.1038/nrc2230. Nat Rev Cancer. 2007. PMID: 17891190 Review.

6

Cyclin D1 mediates resistance to apoptosis through upregulation of molecular chaperones and consequent redistribution of cell death regulators.

Roué G, Pichereau V, Lincet H, Colomer D, Sola B. Roué G, et al. Among authors: colomer d. Oncogene. 2008 Aug 21;27(36):4909-20. doi: 10.1038/onc.2008.126. Epub 2008 Apr 28. Oncogene. 2008. PMID: 18438428

7

BCL-2 phosphorylation modulates sensitivity to the BH3 mimetic GX15-070 (Obatoclax) and reduces its synergistic interaction with bortezomib in chronic lymphocytic leukemia cells.

Pérez-Galán P, Roué G, López-Guerra M, Nguyen M, Villamor N, Montserrat E, Shore GC, Campo E, Colomer D. Pérez-Galán P, et al. Among authors: colomer d. Leukemia. 2008 Sep;22(9):1712-20. doi: 10.1038/leu.2008.175. Epub 2008 Jul 3. Leukemia. 2008. PMID: 18596739

8

Identification of TIGAR in the equilibrative nucleoside transporter 2-mediated response to fludarabine in chronic lymphocytic leukemia cells.

López-Guerra M, Trigueros-Motos L, Molina-Arcas M, Villamor N, Casado FJ, Montserrat E, Campo E, Colomer D, Pastor-Anglada M. López-Guerra M, et al. Among authors: colomer d. Haematologica. 2008 Dec;93(12):1843-51. doi: 10.3324/haematol.13186. Epub 2008 Oct 22. Haematologica. 2008. PMID: 18945750 Free article.

9

Bendamustine is effective in p53-deficient B-cell neoplasms and requires oxidative stress and caspase-independent signaling.

Roué G, López-Guerra M, Milpied P, Pérez-Galán P, Villamor N, Montserrat E, Campo E, Colomer D. Roué G, et al. Among authors: colomer d. Clin Cancer Res. 2008 Nov 1;14(21):6907-15. doi: 10.1158/1078-0432.CCR-08-0388. Clin Cancer Res. 2008. PMID: 18980985

10

p65 activity and ZAP-70 status predict the sensitivity of chronic lymphocytic leukemia cells to the selective IkappaB kinase inhibitor BMS-345541.

López-Guerra M, Roué G, Pérez-Galán P, Alonso R, Villamor N, Montserrat E, Campo E, Colomer D. López-Guerra M, et al. Among authors: colomer d. Clin Cancer Res. 2009 Apr 15;15(8):2767-76. doi: 10.1158/1078-0432.CCR-08-2382. Epub 2009 Apr 7. Clin Cancer Res. 2009. PMID: 19351760

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