Jaako P - Search Results

1

Canonical BMP signaling is dispensable for hematopoietic stem cell function in both adult and fetal liver hematopoiesis, but essential to preserve colon architecture.

Singbrant S, Karlsson G, Ehinger M, Olsson K, Jaako P, Miharada K, Stadtfeld M, Graf T, Karlsson S. Singbrant S, et al. Among authors: jaako p. Blood. 2010 Jun 10;115(23):4689-98. doi: 10.1182/blood-2009-05-220988. Epub 2010 Apr 6. Blood. 2010. PMID: 20371744 Free article.

2

Mice with ribosomal protein S19 deficiency develop bone marrow failure and symptoms like patients with Diamond-Blackfan anemia.

Jaako P, Flygare J, Olsson K, Quere R, Ehinger M, Henson A, Ellis S, Schambach A, Baum C, Richter J, Larsson J, Bryder D, Karlsson S. Jaako P, et al. Blood. 2011 Dec 1;118(23):6087-96. doi: 10.1182/blood-2011-08-371963. Epub 2011 Oct 11. Blood. 2011. PMID: 21989989 Free article.

3

Dietary L-leucine improves the anemia in a mouse model for Diamond-Blackfan anemia.

Jaako P, Debnath S, Olsson K, Bryder D, Flygare J, Karlsson S. Jaako P, et al. Blood. 2012 Sep 13;120(11):2225-8. doi: 10.1182/blood-2012-05-431437. Epub 2012 Jul 12. Blood. 2012. PMID: 22791294 Free article.

4

Gene therapy cures the anemia and lethal bone marrow failure in a mouse model of RPS19-deficient Diamond-Blackfan anemia.

Jaako P, Debnath S, Olsson K, Modlich U, Rothe M, Schambach A, Flygare J, Karlsson S. Jaako P, et al. Haematologica. 2014 Dec;99(12):1792-8. doi: 10.3324/haematol.2014.111195. Epub 2014 Sep 12. Haematologica. 2014. PMID: 25216681 Free PMC article.

5

Disruption of the 5S RNP-Mdm2 interaction significantly improves the erythroid defect in a mouse model for Diamond-Blackfan anemia.

Jaako P, Debnath S, Olsson K, Zhang Y, Flygare J, Lindström MS, Bryder D, Karlsson S. Jaako P, et al. Leukemia. 2015 Nov;29(11):2221-9. doi: 10.1038/leu.2015.128. Epub 2015 May 19. Leukemia. 2015. PMID: 25987256 Free PMC article.

6

Lentiviral Vectors with Cellular Promoters Correct Anemia and Lethal Bone Marrow Failure in a Mouse Model for Diamond-Blackfan Anemia.

Debnath S, Jaako P, Siva K, Rothe M, Chen J, Dahl M, Gaspar HB, Flygare J, Schambach A, Karlsson S. Debnath S, et al. Among authors: jaako p. Mol Ther. 2017 Aug 2;25(8):1805-1814. doi: 10.1016/j.ymthe.2017.04.002. Epub 2017 Apr 20. Mol Ther. 2017. PMID: 28434866 Free PMC article.

7

SPARC is dispensable for murine hematopoiesis, despite its suspected pathophysiological role in 5q-myelodysplastic syndrome.

Siva K, Jaako P, Miharada K, Rörby E, Ehinger M, Karlsson G, Karlsson S. Siva K, et al. Among authors: jaako p. Leukemia. 2012 Nov;26(11):2416-9. doi: 10.1038/leu.2012.97. Epub 2012 Apr 5. Leukemia. 2012. PMID: 22475871 No abstract available.

8

Glucocorticoids improve erythroid progenitor maintenance and dampen Trp53 response in a mouse model of Diamond-Blackfan anaemia.

Sjögren SE, Siva K, Soneji S, George AJ, Winkler M, Jaako P, Wlodarski M, Karlsson S, Hannan RD, Flygare J. Sjögren SE, et al. Among authors: jaako p. Br J Haematol. 2015 Nov;171(4):517-29. doi: 10.1111/bjh.13632. Epub 2015 Aug 25. Br J Haematol. 2015. PMID: 26305041 Free PMC article.

9

Hematopoietic stem cells are intrinsically protected against MLL-ENL-mediated transformation.

Ugale A, Norddahl GL, Wahlestedt M, Säwén P, Jaako P, Pronk CJ, Soneji S, Cammenga J, Bryder D. Ugale A, et al. Among authors: jaako p. Cell Rep. 2014 Nov 20;9(4):1246-55. doi: 10.1016/j.celrep.2014.10.036. Epub 2014 Nov 13. Cell Rep. 2014. PMID: 25456127 Free article.

10

EFL1 mutations impair eIF6 release to cause Shwachman-Diamond syndrome.

Tan S, Kermasson L, Hoslin A, Jaako P, Faille A, Acevedo-Arozena A, Lengline E, Ranta D, Poirée M, Fenneteau O, Ducou le Pointe H, Fumagalli S, Beaupain B, Nitschké P, Bôle-Feysot C, de Villartay JP, Bellanné-Chantelot C, Donadieu J, Kannengiesser C, Warren AJ, Revy P. Tan S, et al. Among authors: jaako p. Blood. 2019 Jul 18;134(3):277-290. doi: 10.1182/blood.2018893404. Epub 2019 May 31. Blood. 2019. PMID: 31151987 Free PMC article.

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