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Loss of ALS-associated TDP-43 in zebrafish causes muscle degeneration, vascular dysfunction, and reduced motor neuron axon outgrowth.
Schmid B, Hruscha A, Hogl S, Banzhaf-Strathmann J, Strecker K, van der Zee J, Teucke M, Eimer S, Hegermann J, Kittelmann M, Kremmer E, Cruts M, Solchenberger B, Hasenkamp L, van Bebber F, Van Broeckhoven C, Edbauer D, Lichtenthaler SF, Haass C. Schmid B, et al. Among authors: hruscha a. Proc Natl Acad Sci U S A. 2013 Mar 26;110(13):4986-91. doi: 10.1073/pnas.1218311110. Epub 2013 Mar 1. Proc Natl Acad Sci U S A. 2013. PMID: 23457265 Free PMC article.
Depletion of pyruvate kinase (PK) activity causes glycolytic intermediate imbalances and reveals a PK-TXNIP regulatory axis.
Nieborak A, Lukauskas S, Capellades J, Heyn P, Santos GS, Motzler K, Zeigerer A, Bester R, Protzer U, Schelter F, Wagner M, Carell T, Hruscha A, Schmid B, Yanes O, Schneider R. Nieborak A, et al. Among authors: hruscha a. Mol Metab. 2023 Aug;74:101748. doi: 10.1016/j.molmet.2023.101748. Epub 2023 Jun 7. Mol Metab. 2023. PMID: 37290673 Free PMC article.
12 results