Takezawa K - Search Results

1

Identification of c-Src as a potential therapeutic target for gastric cancer and of MET activation as a cause of resistance to c-Src inhibition.

Okamoto W, Okamoto I, Yoshida T, Okamoto K, Takezawa K, Hatashita E, Yamada Y, Kuwata K, Arao T, Yanagihara K, Fukuoka M, Nishio K, Nakagawa K. Okamoto W, et al. Among authors: takezawa k. Mol Cancer Ther. 2010 May;9(5):1188-97. doi: 10.1158/1535-7163.MCT-10-0002. Epub 2010 Apr 20. Mol Cancer Ther. 2010. PMID: 20406949

2

Marked anti-tumour activity of the combination of YM155, a novel survivin suppressant, and platinum-based drugs.

Iwasa T, Okamoto I, Takezawa K, Yamanaka K, Nakahara T, Kita A, Koutoku H, Sasamata M, Hatashita E, Yamada Y, Kuwata K, Fukuoka M, Nakagawa K. Iwasa T, et al. Among authors: takezawa k. Br J Cancer. 2010 Jun 29;103(1):36-42. doi: 10.1038/sj.bjc.6605713. Epub 2010 Jun 1. Br J Cancer. 2010. PMID: 20517311 Free PMC article.

3

Identification of thymidylate synthase as a potential therapeutic target for lung cancer.

Takezawa K, Okamoto I, Tsukioka S, Uchida J, Kiniwa M, Fukuoka M, Nakagawa K. Takezawa K, et al. Br J Cancer. 2010 Jul 27;103(3):354-61. doi: 10.1038/sj.bjc.6605793. Epub 2010 Jul 13. Br J Cancer. 2010. PMID: 20628382 Free PMC article.

4

Thymidylate synthase as a determinant of pemetrexed sensitivity in non-small cell lung cancer.

Takezawa K, Okamoto I, Okamoto W, Takeda M, Sakai K, Tsukioka S, Kuwata K, Yamaguchi H, Nishio K, Nakagawa K. Takezawa K, et al. Br J Cancer. 2011 May 10;104(10):1594-601. doi: 10.1038/bjc.2011.129. Epub 2011 Apr 12. Br J Cancer. 2011. PMID: 21487406 Free PMC article.

5

Combined effect of ALK and MEK inhibitors in EML4-ALK-positive non-small-cell lung cancer cells.

Tanizaki J, Okamoto I, Takezawa K, Sakai K, Azuma K, Kuwata K, Yamaguchi H, Hatashita E, Nishio K, Janne PA, Nakagawa K. Tanizaki J, et al. Among authors: takezawa k. Br J Cancer. 2012 Feb 14;106(4):763-7. doi: 10.1038/bjc.2011.586. Epub 2012 Jan 12. Br J Cancer. 2012. PMID: 22240786 Free PMC article.

6

Sorafenib inhibits non-small cell lung cancer cell growth by targeting B-RAF in KRAS wild-type cells and C-RAF in KRAS mutant cells.

Takezawa K, Okamoto I, Yonesaka K, Hatashita E, Yamada Y, Fukuoka M, Nakagawa K. Takezawa K, et al. Cancer Res. 2009 Aug 15;69(16):6515-21. doi: 10.1158/0008-5472.CAN-09-1076. Epub 2009 Jul 28. Cancer Res. 2009. PMID: 19638574

7

Synergistic antitumor effect of S-1 and HER2-targeting agents in gastric cancer with HER2 amplification.

Tanizaki J, Okamoto I, Takezawa K, Tsukioka S, Uchida J, Kiniwa M, Fukuoka M, Nakagawa K. Tanizaki J, et al. Among authors: takezawa k. Mol Cancer Ther. 2010 May;9(5):1198-207. doi: 10.1158/1535-7163.MCT-10-0045. Epub 2010 Apr 27. Mol Cancer Ther. 2010. PMID: 20424000

8

Enhanced anticancer effect of the combination of BIBW2992 and thymidylate synthase-targeted agents in non-small cell lung cancer with the T790M mutation of epidermal growth factor receptor.

Takezawa K, Okamoto I, Tanizaki J, Kuwata K, Yamaguchi H, Fukuoka M, Nishio K, Nakagawa K. Takezawa K, et al. Mol Cancer Ther. 2010 Jun;9(6):1647-56. doi: 10.1158/1535-7163.MCT-09-1009. Epub 2010 Jun 8. Mol Cancer Ther. 2010. PMID: 20530710

9

Role of survivin in EGFR inhibitor-induced apoptosis in non-small cell lung cancers positive for EGFR mutations.

Okamoto K, Okamoto I, Okamoto W, Tanaka K, Takezawa K, Kuwata K, Yamaguchi H, Nishio K, Nakagawa K. Okamoto K, et al. Among authors: takezawa k. Cancer Res. 2010 Dec 15;70(24):10402-10. doi: 10.1158/0008-5472.CAN-10-2438. Cancer Res. 2010. PMID: 21159653

10

Role of ERK-BIM and STAT3-survivin signaling pathways in ALK inhibitor-induced apoptosis in EML4-ALK-positive lung cancer.

Takezawa K, Okamoto I, Nishio K, Jänne PA, Nakagawa K. Takezawa K, et al. Clin Cancer Res. 2011 Apr 15;17(8):2140-8. doi: 10.1158/1078-0432.CCR-10-2798. Epub 2011 Mar 17. Clin Cancer Res. 2011. PMID: 21415216

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