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Page 1
Efficient phagocytosis requires triacylglycerol hydrolysis by adipose triglyceride lipase.
Chandak PG, Radovic B, Aflaki E, Kolb D, Buchebner M, Fröhlich E, Magnes C, Sinner F, Haemmerle G, Zechner R, Tabas I, Levak-Frank S, Kratky D. Chandak PG, et al. Among authors: tabas i. J Biol Chem. 2010 Jun 25;285(26):20192-201. doi: 10.1074/jbc.M110.107854. Epub 2010 Apr 27. J Biol Chem. 2010. PMID: 20424161 Free PMC article.
Macrophages deficient in CTP:Phosphocholine cytidylyltransferase-alpha are viable under normal culture conditions but are highly susceptible to free cholesterol-induced death. Molecular genetic evidence that the induction of phosphatidylcholine biosynthesis in free cholesterol-loaded macrophages is an adaptive response.
Zhang D, Tang W, Yao PM, Yang C, Xie B, Jackowski S, Tabas I. Zhang D, et al. Among authors: tabas i. J Biol Chem. 2000 Nov 10;275(45):35368-76. doi: 10.1074/jbc.M007099200. J Biol Chem. 2000. PMID: 10944538 Free article.
Free cholesterol loading of macrophages is associated with widespread mitochondrial dysfunction and activation of the mitochondrial apoptosis pathway.
Yao PM, Tabas I. Yao PM, et al. Among authors: tabas i. J Biol Chem. 2001 Nov 9;276(45):42468-76. doi: 10.1074/jbc.M101419200. Epub 2001 Aug 31. J Biol Chem. 2001. PMID: 11533046 Free article.
We recently showed that FC loading of macrophages causes apoptosis, approximately 50% of which is mediated by activation of cell-surface FasL and triggering of the Fas pathway (Yao, P. M., and Tabas, I. (2000) J. Biol. Chem. 275, 23807-23813). To elucidate other pat …
We recently showed that FC loading of macrophages causes apoptosis, approximately 50% of which is mediated by activation of cell-surface Fas …
292 results