Hong C - Search Results

1

The E3 ubiquitin ligase IDOL induces the degradation of the low density lipoprotein receptor family members VLDLR and ApoER2.

Hong C, Duit S, Jalonen P, Out R, Scheer L, Sorrentino V, Boyadjian R, Rodenburg KW, Foley E, Korhonen L, Lindholm D, Nimpf J, van Berkel TJ, Tontonoz P, Zelcer N. Hong C, et al. J Biol Chem. 2010 Jun 25;285(26):19720-6. doi: 10.1074/jbc.M110.123729. Epub 2010 Apr 28. J Biol Chem. 2010. PMID: 20427281 Free PMC article.

2

The arginase II gene is an anti-inflammatory target of liver X receptor in macrophages.

Marathe C, Bradley MN, Hong C, Lopez F, Ruiz de Galarreta CM, Tontonoz P, Castrillo A. Marathe C, et al. Among authors: hong c. J Biol Chem. 2006 Oct 27;281(43):32197-206. doi: 10.1074/jbc.M605237200. Epub 2006 Aug 30. J Biol Chem. 2006. PMID: 16943198 Free article.

3

LXR regulates cholesterol uptake through Idol-dependent ubiquitination of the LDL receptor.

Zelcer N, Hong C, Boyadjian R, Tontonoz P. Zelcer N, et al. Among authors: hong c. Science. 2009 Jul 3;325(5936):100-4. doi: 10.1126/science.1168974. Epub 2009 Jun 11. Science. 2009. PMID: 19520913 Free PMC article.

4

Targeted disruption of the idol gene alters cellular regulation of the low-density lipoprotein receptor by sterols and liver x receptor agonists.

Scotti E, Hong C, Yoshinaga Y, Tu Y, Hu Y, Zelcer N, Boyadjian R, de Jong PJ, Young SG, Fong LG, Tontonoz P. Scotti E, et al. Among authors: hong c. Mol Cell Biol. 2011 May;31(9):1885-93. doi: 10.1128/MCB.01469-10. Epub 2011 Feb 22. Mol Cell Biol. 2011. PMID: 21343340 Free PMC article.

5

HRASLS3 is a PPARgamma-selective target gene that promotes adipocyte differentiation.

Hummasti S, Hong C, Bensinger SJ, Tontonoz P. Hummasti S, et al. Among authors: hong c. J Lipid Res. 2008 Dec;49(12):2535-44. doi: 10.1194/jlr.M800269-JLR200. Epub 2008 Jul 29. J Lipid Res. 2008. PMID: 18664718 Free PMC article.

6

Coordination of inflammation and metabolism by PPAR and LXR nuclear receptors.

Hong C, Tontonoz P. Hong C, et al. Curr Opin Genet Dev. 2008 Oct;18(5):461-7. doi: 10.1016/j.gde.2008.07.016. Epub 2008 Sep 7. Curr Opin Genet Dev. 2008. PMID: 18782619 Free PMC article. Review.

7

Constitutive activation of LXR in macrophages regulates metabolic and inflammatory gene expression: identification of ARL7 as a direct target.

Hong C, Walczak R, Dhamko H, Bradley MN, Marathe C, Boyadjian R, Salazar JV, Tontonoz P. Hong C, et al. J Lipid Res. 2011 Mar;52(3):531-9. doi: 10.1194/jlr.M010686. Epub 2010 Dec 27. J Lipid Res. 2011. PMID: 21187453 Free PMC article.

8

The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor.

Zhang L, Fairall L, Goult BT, Calkin AC, Hong C, Millard CJ, Tontonoz P, Schwabe JW. Zhang L, et al. Among authors: hong c. Genes Dev. 2011 Jun 15;25(12):1262-74. doi: 10.1101/gad.2056211. Genes Dev. 2011. PMID: 21685362 Free PMC article.

9

FERM-dependent E3 ligase recognition is a conserved mechanism for targeted degradation of lipoprotein receptors.

Calkin AC, Goult BT, Zhang L, Fairall L, Hong C, Schwabe JW, Tontonoz P. Calkin AC, et al. Among authors: hong c. Proc Natl Acad Sci U S A. 2011 Dec 13;108(50):20107-12. doi: 10.1073/pnas.1111589108. Epub 2011 Nov 22. Proc Natl Acad Sci U S A. 2011. PMID: 22109552 Free PMC article.

10

LXRα is uniquely required for maximal reverse cholesterol transport and atheroprotection in ApoE-deficient mice.

Hong C, Bradley MN, Rong X, Wang X, Wagner A, Grijalva V, Castellani LW, Salazar J, Realegeno S, Boyadjian R, Fogelman AM, Van Lenten BJ, Reddy ST, Lusis AJ, Tangirala RK, Tontonoz P. Hong C, et al. J Lipid Res. 2012 Jun;53(6):1126-33. doi: 10.1194/jlr.M022061. Epub 2012 Mar 26. J Lipid Res. 2012. PMID: 22454476 Free PMC article.

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