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Knockdown of Ketohexokinase Versus Inhibition of Its Kinase Activity Exert Divergent Effects on Fructose Metabolism.
Park SH, Fadhul T, Conroy LR, Clarke HA, Sun RC, Wallenius K, Boucher J, O'Mahony G, Boianelli A, Persson M, Jung S, Jang C, Loria AS, Martinez GJ, Kipp ZA, Bates EA, Hinds TD Jr, Divanovic S, Softic S. Park SH, et al. Among authors: hinds td jr. JCI Insight. 2024 Oct 17:e184396. doi: 10.1172/jci.insight.184396. Online ahead of print. JCI Insight. 2024. PMID: 39418102 Free article.
Conditional deletion of CEACAM1 in hepatic stellate cells causes their activation.
Muturi HT, Ghadieh HE, Asalla S, Lester SG, Belew GD, Zaidi S, Abdolahipour R, Shrestha AP, Portuphy AO, Stankus HL, Helal RA, Verhulst S, Duarte S, Zarrinpar A, van Grunsven LA, Friedman SL, Schwabe RF, Hinds TD Jr, Kumarasamy S, Najjar SM. Muturi HT, et al. Among authors: hinds td jr. Mol Metab. 2024 Oct;88:102010. doi: 10.1016/j.molmet.2024.102010. Epub 2024 Aug 19. Mol Metab. 2024. PMID: 39168268 Free PMC article.
FOXS1 is increased in liver fibrosis and regulates TGFβ responsiveness and proliferation pathways in human hepatic stellate cells.
Bates EA, Kipp ZA, Lee WH, Martinez GJ, Weaver L, Becker KN, Pauss SN, Creeden JF, Anspach GB, Helsley RN, Xu M, Bruno MEC, Starr ME, Hinds TD Jr. Bates EA, et al. Among authors: hinds td jr. J Biol Chem. 2024 Mar;300(3):105691. doi: 10.1016/j.jbc.2024.105691. Epub 2024 Jan 26. J Biol Chem. 2024. PMID: 38280429 Free PMC article.
Loss of carnitine palmitoyltransferase 1a reduces docosahexaenoic acid-containing phospholipids and drives sexually dimorphic liver disease in mice.
Zelows MM, Cady C, Dharanipragada N, Mead AE, Kipp ZA, Bates EA, Varadharajan V, Banerjee R, Park SH, Shelman NR, Clarke HA, Hawkinson TR, Medina T, Sun RC, Lydic TA, Hinds TD Jr, Brown JM, Softic S, Graf GA, Helsley RN. Zelows MM, et al. Among authors: hinds td jr. Mol Metab. 2023 Dec;78:101815. doi: 10.1016/j.molmet.2023.101815. Epub 2023 Oct 4. Mol Metab. 2023. PMID: 37797918 Free PMC article.
Loss of hepatic PPARα in mice causes hypertension and cardiovascular disease.
Badmus OO, Kipp ZA, Bates EA, da Silva AA, Taylor LC, Martinez GJ, Lee WH, Creeden JF, Hinds TD Jr, Stec DE. Badmus OO, et al. Among authors: hinds td jr. Am J Physiol Regul Integr Comp Physiol. 2023 Jul 1;325(1):R81-R95. doi: 10.1152/ajpregu.00057.2023. Epub 2023 May 22. Am J Physiol Regul Integr Comp Physiol. 2023. PMID: 37212551 Free PMC article.
75 results