The pregnane X receptor locus is associated with susceptibility to inflammatory bowel disease.
Dring MM, Goulding CA, Trimble VI, Keegan D, Ryan AW, Brophy KM, Smyth CM, Keeling PW, O'Donoghue D, O'Sullivan M, O'Morain C, Mahmud N, Wikström AC, Kelleher D, McManus R.
Dring MM, et al.
Gastroenterology. 2006 Feb;130(2):341-8; quiz 592. doi: 10.1053/j.gastro.2005.12.008.
Gastroenterology. 2006.
PMID: 16472590