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Genetic inactivation of the Fanconi anemia gene FANCC identified in the hepatocellular carcinoma cell line HuH-7 confers sensitivity towards DNA-interstrand crosslinking agents.
Palagyi A, Neveling K, Plinninger U, Ziesch A, Targosz BS, Denk GU, Ochs S, Rizzani A, Meier D, Thasler WE, Hanenberg H, De Toni EN, Bassermann F, Schäfer C, Göke B, Schindler D, Gallmeier E. Palagyi A, et al. Among authors: schindler d. Mol Cancer. 2010 May 28;9:127. doi: 10.1186/1476-4598-9-127. Mol Cancer. 2010. PMID: 20509860 Free PMC article.
A common founder mutation in FANCA underlies the world's highest prevalence of Fanconi anemia in Gypsy families from Spain.
Callén E, Casado JA, Tischkowitz MD, Bueren JA, Creus A, Marcos R, Dasí A, Estella JM, Muñoz A, Ortega JJ, de Winter J, Joenje H, Schindler D, Hanenberg H, Hodgson SV, Mathew CG, Surrallés J. Callén E, et al. Among authors: schindler d. Blood. 2005 Mar 1;105(5):1946-9. doi: 10.1182/blood-2004-07-2588. Epub 2004 Nov 2. Blood. 2005. PMID: 15522956 Free article.
The BRCA1-interacting helicase BRIP1 is deficient in Fanconi anemia.
Levran O, Attwooll C, Henry RT, Milton KL, Neveling K, Rio P, Batish SD, Kalb R, Velleuer E, Barral S, Ott J, Petrini J, Schindler D, Hanenberg H, Auerbach AD. Levran O, et al. Among authors: schindler d. Nat Genet. 2005 Sep;37(9):931-3. doi: 10.1038/ng1624. Epub 2005 Aug 21. Nat Genet. 2005. PMID: 16116424
Fanconi anaemia - response to Manoharan.
Hanenberg H, Huck K, Gudowius S, Göbel U, Kobbe G, Haas R, Kalb R, Neveling K, Schindler D. Hanenberg H, et al. Among authors: schindler d. Br J Haematol. 2006 Oct;135(1):139-40. doi: 10.1111/j.1365-2141.2006.06263.x. Epub 2006 Aug 22. Br J Haematol. 2006. PMID: 16925571 Free article. No abstract available.
523 results