Amalfitano A - Search Results

1

Adenovirus capsid-display of the retro-oriented human complement inhibitor DAF reduces Ad vector-triggered immune responses in vitro and in vivo.

Seregin SS, Aldhamen YA, Appledorn DM, Hartman ZC, Schuldt NJ, Scott J, Godbehere S, Jiang H, Frank MM, Amalfitano A. Seregin SS, et al. Among authors: amalfitano a. Blood. 2010 Sep 9;116(10):1669-77. doi: 10.1182/blood-2010-03-276949. Epub 2010 May 28. Blood. 2010. PMID: 20511542 Free PMC article.

2

Adenovirus vector-induced innate inflammatory mediators, MAPK signaling, as well as adaptive immune responses are dependent upon both TLR2 and TLR9 in vivo.

Appledorn DM, Patial S, McBride A, Godbehere S, Van Rooijen N, Parameswaran N, Amalfitano A. Appledorn DM, et al. Among authors: amalfitano a. J Immunol. 2008 Aug 1;181(3):2134-44. doi: 10.4049/jimmunol.181.3.2134. J Immunol. 2008. PMID: 18641352

3

Transient pretreatment with glucocorticoid ablates innate toxicity of systemically delivered adenoviral vectors without reducing efficacy.

Seregin SS, Appledorn DM, McBride AJ, Schuldt NJ, Aldhamen YA, Voss T, Wei J, Bujold M, Nance W, Godbehere S, Amalfitano A. Seregin SS, et al. Among authors: amalfitano a. Mol Ther. 2009 Apr;17(4):685-96. doi: 10.1038/mt.2008.297. Epub 2009 Jan 27. Mol Ther. 2009. PMID: 19174760 Free PMC article.

4

Overcoming pre-existing adenovirus immunity by genetic engineering of adenovirus-based vectors.

Seregin SS, Amalfitano A. Seregin SS, et al. Among authors: amalfitano a. Expert Opin Biol Ther. 2009 Dec;9(12):1521-31. doi: 10.1517/14712590903307388. Expert Opin Biol Ther. 2009. PMID: 19780714 Review.

5

beta-Arrestins modulate Adenovirus-vector-induced innate immune responses: differential regulation by beta-arrestin-1 and beta-arrestin-2.

Seregin SS, Appledorn DM, Patial S, Bujold M, Nance W, Godbehere S, Parameswaran N, Amalfitano A. Seregin SS, et al. Among authors: amalfitano a. Virus Res. 2010 Jan;147(1):123-34. doi: 10.1016/j.virusres.2009.10.023. Epub 2009 Nov 6. Virus Res. 2010. PMID: 19896992 Free PMC article.

6

A new adenovirus based vaccine vector expressing an Eimeria tenella derived TLR agonist improves cellular immune responses to an antigenic target.

Appledorn DM, Aldhamen YA, Depas W, Seregin SS, Liu CJ, Schuldt N, Quach D, Quiroga D, Godbehere S, Zlatkin I, Kim S, McCormick JJ, Amalfitano A. Appledorn DM, et al. Among authors: amalfitano a. PLoS One. 2010 Mar 8;5(3):e9579. doi: 10.1371/journal.pone.0009579. PLoS One. 2010. PMID: 20221448 Free PMC article.

7

Novel adenovirus vectors 'capsid-displaying' a human complement inhibitor.

Seregin SS, Hartman ZC, Appledorn DM, Godbehere S, Jiang H, Frank MM, Amalfitano A. Seregin SS, et al. Among authors: amalfitano a. J Innate Immun. 2010;2(4):353-9. doi: 10.1159/000284368. Epub 2010 Feb 11. J Innate Immun. 2010. PMID: 20375551 Free PMC article.

8

Sublingual administration of an adenovirus serotype 5 (Ad5)-based vaccine confirms Toll-like receptor agonist activity in the oral cavity and elicits improved mucosal and systemic cell-mediated responses against HIV antigens despite preexisting Ad5 immunity.

Appledorn DM, Aldhamen YA, Godbehere S, Seregin SS, Amalfitano A. Appledorn DM, et al. Among authors: amalfitano a. Clin Vaccine Immunol. 2011 Jan;18(1):150-60. doi: 10.1128/CVI.00341-10. Epub 2010 Nov 17. Clin Vaccine Immunol. 2011. PMID: 21084461 Free PMC article.

9

Expression of the SLAM family of receptors adapter EAT-2 as a novel strategy for enhancing beneficial immune responses to vaccine antigens.

Aldhamen YA, Appledorn DM, Seregin SS, Liu CJ, Schuldt NJ, Godbehere S, Amalfitano A. Aldhamen YA, et al. Among authors: amalfitano a. J Immunol. 2011 Jan 15;186(2):722-32. doi: 10.4049/jimmunol.1002105. Epub 2010 Dec 13. J Immunol. 2011. PMID: 21149608 Free PMC article.

10

Use of DAF-displaying adenovirus vectors reduces induction of transgene- and vector-specific adaptive immune responses in mice.

Seregin SS, Aldhamen YA, Appledorn DM, Zehnder J, Voss T, Godbehere S, Amalfitano A. Seregin SS, et al. Among authors: amalfitano a. Hum Gene Ther. 2011 Sep;22(9):1083-94. doi: 10.1089/hum.2010.218. Epub 2011 Apr 18. Hum Gene Ther. 2011. PMID: 21388344 Free PMC article.

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