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Osteoclasts from patients with autosomal dominant osteopetrosis type I caused by a T253I mutation in low-density lipoprotein receptor-related protein 5 are normal in vitro, but have decreased resorption capacity in vivo.
Henriksen K, Gram J, Høegh-Andersen P, Jemtland R, Ueland T, Dziegiel MH, Schaller S, Bollerslev J, Karsdal MA. Henriksen K, et al. Among authors: dziegiel mh. Am J Pathol. 2005 Nov;167(5):1341-8. doi: 10.1016/S0002-9440(10)61221-7. Am J Pathol. 2005. PMID: 16251418 Free PMC article.
131 results