Pryor KD - Search Results

1

Peptidomic profiling of human cerebrospinal fluid identifies YPRPIHPA as a novel substrate for prolylcarboxypeptidase.

Zhao X, Southwick K, Cardasis HL, Du Y, Lassman ME, Xie D, El-Sherbeini M, Geissler WM, Pryor KD, Verras A, Garcia-Calvo M, Shen DM, Yates NA, Pinto S, Hendrickon RC. Zhao X, et al. Among authors: pryor kd. Proteomics. 2010 Aug;10(15):2882-6. doi: 10.1002/pmic.201000145. Proteomics. 2010. PMID: 20517885

2

Design and synthesis of prolylcarboxypeptidase (PrCP) inhibitors to validate PrCP as a potential target for obesity.

Zhou C, Garcia-Calvo M, Pinto S, Lombardo M, Feng Z, Bender K, Pryor KD, Bhatt UR, Chabin RM, Geissler WM, Shen Z, Tong X, Zhang Z, Wong KK, Roy RS, Chapman KT, Yang L, Xiong Y. Zhou C, et al. Among authors: pryor kd. J Med Chem. 2010 Oct 14;53(19):7251-63. doi: 10.1021/jm101013m. J Med Chem. 2010. PMID: 20857914

3

Catalytic properties and inhibition of proline-specific dipeptidyl peptidases II, IV and VII.

Leiting B, Pryor KD, Wu JK, Marsilio F, Patel RA, Craik CS, Ellman JA, Cummings RT, Thornberry NA. Leiting B, et al. Among authors: pryor kd. Biochem J. 2003 Apr 15;371(Pt 2):525-32. doi: 10.1042/BJ20021643. Biochem J. 2003. PMID: 12529175 Free PMC article.

4

Discovery of potent and selective dipeptidyl peptidase IV inhibitors derived from beta-aminoamides bearing subsituted triazolopiperazines.

Kim D, Kowalchick JE, Brockunier LL, Parmee ER, Eiermann GJ, Fisher MH, He H, Leiting B, Lyons K, Scapin G, Patel SB, Petrov A, Pryor KD, Roy RS, Wu JK, Zhang X, Wyvratt MJ, Zhang BB, Zhu L, Thornberry NA, Weber AE. Kim D, et al. Among authors: pryor kd. J Med Chem. 2008 Feb 14;51(3):589-602. doi: 10.1021/jm070330v. Epub 2008 Jan 18. J Med Chem. 2008. PMID: 18201067

5

Triazolopiperazine-amides as dipeptidyl peptidase IV inhibitors: close analogs of JANUVIA (sitagliptin phosphate).

Kim D, Kowalchick JE, Edmondson SD, Mastracchio A, Xu J, Eiermann GJ, Leiting B, Wu JK, Pryor KD, Patel RA, He H, Lyons KA, Thornberry NA, Weber AE. Kim D, et al. Among authors: pryor kd. Bioorg Med Chem Lett. 2007 Jun 15;17(12):3373-7. doi: 10.1016/j.bmcl.2007.03.098. Epub 2007 Apr 5. Bioorg Med Chem Lett. 2007. PMID: 17434732

6

A high quality nuclear magnetic resonance solution structure of peptide deformylase from Escherichia coli: application of an automated assignment strategy using GARANT.

O'Connell JF, Pryor KD, Grant SK, Leiting B. O'Connell JF, et al. Among authors: pryor kd. J Biomol NMR. 1999 Apr;13(4):311-24. doi: 10.1023/a:1008311502626. J Biomol NMR. 1999. PMID: 10353194

7

Design, synthesis, and biological evaluation of triazolopiperazine-based beta-amino amides as potent, orally active dipeptidyl peptidase IV (DPP-4) inhibitors.

Kowalchick JE, Leiting B, Pryor KD, Marsilio F, Wu JK, He H, Lyons KA, Eiermann GJ, Petrov A, Scapin G, Patel RA, Thornberry NA, Weber AE, Kim D. Kowalchick JE, et al. Among authors: pryor kd. Bioorg Med Chem Lett. 2007 Nov 1;17(21):5934-9. doi: 10.1016/j.bmcl.2007.07.100. Epub 2007 Aug 23. Bioorg Med Chem Lett. 2007. PMID: 17827003

8

High-level expression of soluble protein in Escherichia coli using a His6-tag and maltose-binding-protein double-affinity fusion system.

Pryor KD, Leiting B. Pryor KD, et al. Protein Expr Purif. 1997 Aug;10(3):309-19. doi: 10.1006/prep.1997.0759. Protein Expr Purif. 1997. PMID: 9268677

9

Inhibition of dipeptidyl-peptidase IV does not increase circulating IGF-1 concentrations in growing pigs.

Faidley TD, Leiting B, Pryor KD, Lyons K, Hickey GJ, Thompson DR. Faidley TD, et al. Among authors: pryor kd. Exp Biol Med (Maywood). 2006 Sep;231(8):1373-8. doi: 10.1177/153537020623100811. Exp Biol Med (Maywood). 2006. PMID: 16946406

10

Soluble penicillin-binding protein 2a: beta-lactam binding and inhibition by non-beta-lactams using a 96-well format.

Toney JH, Hammond GG, Leiting B, Pryor KD, Wu JK, Cuca GC, Pompliano DL. Toney JH, et al. Among authors: pryor kd. Anal Biochem. 1998 Jan 1;255(1):113-9. doi: 10.1006/abio.1997.2458. Anal Biochem. 1998. PMID: 9448849

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