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Master donor viruses A/Leningrad/134/17/57 (H2N2) and B/USSR/60/69 and derived reassortants used in live attenuated influenza vaccine (LAIV) do not display neurovirulent properties in a mouse model.
Voeten JT, Kiseleva IV, Glansbeek HL, Basten SM, Drieszen-van der Cruijsen SK, Rudenko LG, van den Bosch H, Heldens JG. Voeten JT, et al. Among authors: heldens jg. Arch Virol. 2010 Sep;155(9):1391-9. doi: 10.1007/s00705-010-0719-8. Epub 2010 Jun 10. Arch Virol. 2010. PMID: 20532926 Free article.
Genetic bases of the temperature-sensitive phenotype of a master donor virus used in live attenuated influenza vaccines: A/Leningrad/134/17/57 (H2N2).
Isakova-Sivak I, Chen LM, Matsuoka Y, Voeten JT, Kiseleva I, Heldens JG, den Bosch Hv, Klimov A, Rudenko L, Cox NJ, Donis RO. Isakova-Sivak I, et al. Among authors: heldens jg. Virology. 2011 Apr 10;412(2):297-305. doi: 10.1016/j.virol.2011.01.004. Epub 2011 Feb 18. Virology. 2011. PMID: 21315402 Free article.
Characterization of reverse genetics-derived cold-adapted master donor virus A/Leningrad/134/17/57 (H2N2) and reassortants with H5N1 surface genes in a mouse model.
Isakova-Sivak I, Chen LM, Bourgeois M, Matsuoka Y, Voeten JT, Heldens JG, van den Bosch H, Klimov A, Rudenko L, Cox NJ, Donis RO. Isakova-Sivak I, et al. Among authors: heldens jg. Clin Vaccine Immunol. 2014 May;21(5):722-31. doi: 10.1128/CVI.00819-13. Epub 2014 Mar 19. Clin Vaccine Immunol. 2014. PMID: 24648485 Free PMC article.
Comparative immunogenicity and cross-clade protective efficacy of mammalian cell-grown inactivated and live attenuated H5N1 reassortant vaccines in ferrets.
Gustin KM, Maines TR, Belser JA, van Hoeven N, Lu X, Dong L, Isakova-Sivak I, Chen LM, Voeten JT, Heldens JG, van den Bosch H, Cox NJ, Tumpey TM, Klimov AI, Rudenko L, Donis RO, Katz JM. Gustin KM, et al. Among authors: heldens jg. J Infect Dis. 2011 Nov 15;204(10):1491-9. doi: 10.1093/infdis/jir596. Epub 2011 Sep 28. J Infect Dis. 2011. PMID: 21957153
47 results