Smith RA - Search Results

1

Identification of S-nitrosated mitochondrial proteins by S-nitrosothiol difference in gel electrophoresis (SNO-DIGE): implications for the regulation of mitochondrial function by reversible S-nitrosation.

Chouchani ET, Hurd TR, Nadtochiy SM, Brookes PS, Fearnley IM, Lilley KS, Smith RA, Murphy MP. Chouchani ET, et al. Among authors: smith ra. Biochem J. 2010 Aug 15;430(1):49-59. doi: 10.1042/BJ20100633. Biochem J. 2010. PMID: 20533907 Free PMC article.

2

A mitochondria-targeted S-nitrosothiol modulates respiration, nitrosates thiols, and protects against ischemia-reperfusion injury.

Prime TA, Blaikie FH, Evans C, Nadtochiy SM, James AM, Dahm CC, Vitturi DA, Patel RP, Hiley CR, Abakumova I, Requejo R, Chouchani ET, Hurd TR, Garvey JF, Taylor CT, Brookes PS, Smith RA, Murphy MP. Prime TA, et al. Among authors: smith ra. Proc Natl Acad Sci U S A. 2009 Jun 30;106(26):10764-9. doi: 10.1073/pnas.0903250106. Epub 2009 Jun 15. Proc Natl Acad Sci U S A. 2009. PMID: 19528654 Free PMC article.

3

Cardioprotection by S-nitrosation of a cysteine switch on mitochondrial complex I.

Chouchani ET, Methner C, Nadtochiy SM, Logan A, Pell VR, Ding S, James AM, Cochemé HM, Reinhold J, Lilley KS, Partridge L, Fearnley IM, Robinson AJ, Hartley RC, Smith RA, Krieg T, Brookes PS, Murphy MP. Chouchani ET, et al. Among authors: smith ra. Nat Med. 2013 Jun;19(6):753-9. doi: 10.1038/nm.3212. Epub 2013 May 26. Nat Med. 2013. PMID: 23708290 Free PMC article.

4

Antioxidant and prooxidant properties of mitochondrial Coenzyme Q.

James AM, Smith RA, Murphy MP. James AM, et al. Among authors: smith ra. Arch Biochem Biophys. 2004 Mar 1;423(1):47-56. doi: 10.1016/j.abb.2003.12.025. Arch Biochem Biophys. 2004. PMID: 14989264 Review.

5

Cell-penetrating peptides do not cross mitochondrial membranes even when conjugated to a lipophilic cation: evidence against direct passage through phospholipid bilayers.

Ross MF, Filipovska A, Smith RA, Gait MJ, Murphy MP. Ross MF, et al. Among authors: smith ra. Biochem J. 2004 Nov 1;383(Pt. 3):457-68. doi: 10.1042/BJ20041095. Biochem J. 2004. PMID: 15270716 Free PMC article.

6

Accumulation of lipophilic dications by mitochondria and cells.

Ross MF, Da Ros T, Blaikie FH, Prime TA, Porteous CM, Severina II, Skulachev VP, Kjaergaard HG, Smith RA, Murphy MP. Ross MF, et al. Among authors: smith ra. Biochem J. 2006 Nov 15;400(1):199-208. doi: 10.1042/BJ20060919. Biochem J. 2006. PMID: 16948637 Free PMC article.

7

Targeting antioxidants to mitochondria by conjugation to lipophilic cations.

Murphy MP, Smith RA. Murphy MP, et al. Among authors: smith ra. Annu Rev Pharmacol Toxicol. 2007;47:629-56. doi: 10.1146/annurev.pharmtox.47.120505.105110. Annu Rev Pharmacol Toxicol. 2007. PMID: 17014364 Review.

8

Rapid and extensive uptake and activation of hydrophobic triphenylphosphonium cations within cells.

Ross MF, Prime TA, Abakumova I, James AM, Porteous CM, Smith RA, Murphy MP. Ross MF, et al. Among authors: smith ra. Biochem J. 2008 May 1;411(3):633-45. doi: 10.1042/BJ20080063. Biochem J. 2008. PMID: 18294140

9

Mitochondrial accumulation of a lipophilic cation conjugated to an ionisable group depends on membrane potential, pH gradient and pK(a): implications for the design of mitochondrial probes and therapies.

Finichiu PG, James AM, Larsen L, Smith RA, Murphy MP. Finichiu PG, et al. Among authors: smith ra. J Bioenerg Biomembr. 2013 Feb;45(1-2):165-73. doi: 10.1007/s10863-012-9493-5. Epub 2012 Nov 22. J Bioenerg Biomembr. 2013. PMID: 23180142

10

Protection through postconditioning or a mitochondria-targeted S-nitrosothiol is unaffected by cardiomyocyte-selective ablation of protein kinase G.

Methner C, Lukowski R, Grube K, Loga F, Smith RA, Murphy MP, Hofmann F, Krieg T. Methner C, et al. Among authors: smith ra. Basic Res Cardiol. 2013 Mar;108(2):337. doi: 10.1007/s00395-013-0337-1. Epub 2013 Feb 20. Basic Res Cardiol. 2013. PMID: 23423145

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