A data processing pipeline for mammalian proteome dynamics studies using stable isotope metabolic labeling.
Guan S, Price JC, Prusiner SB, Ghaemmaghami S, Burlingame AL.
Guan S, et al.
Mol Cell Proteomics. 2011 Dec;10(12):M111.010728. doi: 10.1074/mcp.M111.010728. Epub 2011 Sep 21.
Mol Cell Proteomics. 2011.
PMID: 21937731
Free PMC article.
In a recent study, in vivo metabolic labeling using (15)N traced the rate of label incorporation among more than 1700 proteins simultaneously and enabled the determination of individual protein turnover rate constants over a dynamic range of three orders of magnitude (Price, J. C …
In a recent study, in vivo metabolic labeling using (15)N traced the rate of label incorporation among more than 1700 proteins simultaneousl …