Stanton R - Search Results

1

Enhanced selectivity profile of pyrazole-urea based DFG-out p38alpha inhibitors.

Liu H, Kuhn C, Feru F, Jacques SL, Deshmukh GD, Ye P, Rennie GR, Johnson T, Kazmirski S, Low S, Coli R, Ding YH, Cheng AC, Tecle H, English JM, Stanton R, Wu JC. Liu H, et al. Among authors: stanton r. Bioorg Med Chem Lett. 2010 Aug 15;20(16):4885-91. doi: 10.1016/j.bmcl.2010.06.073. Epub 2010 Jun 17. Bioorg Med Chem Lett. 2010. PMID: 20620059

2

Potent and selective thiophene urea-templated inhibitors of S6K.

Ye P, Kuhn C, Juan M, Sharma R, Connolly B, Alton G, Liu H, Stanton R, Kablaoui NM. Ye P, et al. Among authors: stanton r. Bioorg Med Chem Lett. 2011 Jan 15;21(2):849-52. doi: 10.1016/j.bmcl.2010.11.069. Epub 2010 Nov 21. Bioorg Med Chem Lett. 2011. PMID: 21185721

3

Application of Free-Wilson selectivity analysis for combinatorial library design.

Sciabola S, Stanton RV, Johnson TL, Xi H. Sciabola S, et al. Methods Mol Biol. 2011;685:91-109. doi: 10.1007/978-1-60761-931-4_5. Methods Mol Biol. 2011. PMID: 20981520

4

Molecular dynamics simulation and binding energy calculation for estimation of oligonucleotide duplex thermostability in RNA-based therapeutics.

Shen L, Johnson TL, Clugston S, Huang H, Butenhof KJ, Stanton RV. Shen L, et al. J Chem Inf Model. 2011 Aug 22;51(8):1957-65. doi: 10.1021/ci200141j. Epub 2011 Jul 20. J Chem Inf Model. 2011. PMID: 21702481

5

Evaluation of a novel shape-based computational filter for lead evolution: application to thrombin inhibitors.

Srinivasan J, Castellino A, Bradley EK, Eksterowicz JE, Grootenhuis PD, Putta S, Stanton RV. Srinivasan J, et al. J Med Chem. 2002 Jun 6;45(12):2494-500. doi: 10.1021/jm010494q. J Med Chem. 2002. PMID: 12036357

6

Identification of small-molecule inhibitors of the JIP-JNK interaction.

Chen T, Kablaoui N, Little J, Timofeevski S, Tschantz WR, Chen P, Feng J, Charlton M, Stanton R, Bauer P. Chen T, et al. Among authors: stanton r. Biochem J. 2009 May 13;420(2):283-94. doi: 10.1042/BJ20081899. Biochem J. 2009. PMID: 19243309

7

Discovery and gram-scale synthesis of BMS-593214, a potent, selective FVIIa inhibitor.

Priestley ES, De Lucca I, Zhou J, Zhou J, Saiah E, Stanton R, Robinson L, Luettgen JM, Wei A, Wen X, Knabb RM, Wong PC, Wexler RR. Priestley ES, et al. Among authors: stanton r. Bioorg Med Chem Lett. 2013 Apr 15;23(8):2432-5. doi: 10.1016/j.bmcl.2013.02.013. Epub 2013 Feb 14. Bioorg Med Chem Lett. 2013. PMID: 23478148

8

Performance of 3D-database molecular docking studies into homology models.

Oshiro C, Bradley EK, Eksterowicz J, Evensen E, Lamb ML, Lanctot JK, Putta S, Stanton R, Grootenhuis PD. Oshiro C, et al. Among authors: stanton r. J Med Chem. 2004 Jan 29;47(3):764-7. doi: 10.1021/jm0300781. J Med Chem. 2004. PMID: 14736258

9

Helixconstraints and amino acid substitution in GLP-1 increase cAMP and insulin secretion but not beta-arrestin 2 signaling.

Plisson F, Hill TA, Mitchell JM, Hoang HN, de Araujo AD, Xu W, Cotterell A, Edmonds DJ, Stanton RV, Derksen DR, Loria PM, Griffith DA, Price DA, Liras S, Fairlie DP. Plisson F, et al. Among authors: stanton rv. Eur J Med Chem. 2017 Feb 15;127:703-714. doi: 10.1016/j.ejmech.2016.10.044. Epub 2016 Oct 21. Eur J Med Chem. 2017. PMID: 27823886

10

Predicting kinase selectivity profiles using Free-Wilson QSAR analysis.

Sciabola S, Stanton RV, Wittkopp S, Wildman S, Moshinsky D, Potluri S, Xi H. Sciabola S, et al. J Chem Inf Model. 2008 Sep;48(9):1851-67. doi: 10.1021/ci800138n. Epub 2008 Aug 22. J Chem Inf Model. 2008. PMID: 18717582

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