Tarsounas M - Search Results

1

Mammalian Rap1 controls telomere function and gene expression through binding to telomeric and extratelomeric sites.

Martinez P, Thanasoula M, Carlos AR, Gómez-López G, Tejera AM, Schoeftner S, Dominguez O, Pisano DG, Tarsounas M, Blasco MA. Martinez P, et al. Among authors: tarsounas m. Nat Cell Biol. 2010 Aug;12(8):768-80. doi: 10.1038/ncb2081. Epub 2010 Jul 11. Nat Cell Biol. 2010. PMID: 20622869 Free PMC article.

2

Telomere maintenance requires the RAD51D recombination/repair protein.

Tarsounas M, Muñoz P, Claas A, Smiraldo PG, Pittman DL, Blasco MA, West SC. Tarsounas M, et al. Cell. 2004 Apr 30;117(3):337-47. doi: 10.1016/s0092-8674(04)00337-x. Cell. 2004. PMID: 15109494 Free article.

3

RAD51C facilitates checkpoint signaling by promoting CHK2 phosphorylation.

Badie S, Liao C, Thanasoula M, Barber P, Hill MA, Tarsounas M. Badie S, et al. Among authors: tarsounas m. J Cell Biol. 2009 May 18;185(4):587-600. doi: 10.1083/jcb.200811079. J Cell Biol. 2009. PMID: 19451272 Free PMC article.

4

Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice.

Martínez P, Thanasoula M, Muñoz P, Liao C, Tejera A, McNees C, Flores JM, Fernández-Capetillo O, Tarsounas M, Blasco MA. Martínez P, et al. Among authors: tarsounas m. Genes Dev. 2009 Sep 1;23(17):2060-75. doi: 10.1101/gad.543509. Epub 2009 Aug 13. Genes Dev. 2009. PMID: 19679647 Free PMC article.

5

p53 prevents entry into mitosis with uncapped telomeres.

Thanasoula M, Escandell JM, Martinez P, Badie S, Muñoz P, Blasco MA, Tarsounas M. Thanasoula M, et al. Among authors: tarsounas m. Curr Biol. 2010 Mar 23;20(6):521-6. doi: 10.1016/j.cub.2010.01.046. Epub 2010 Mar 11. Curr Biol. 2010. PMID: 20226664 Free PMC article.

6

53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers.

Bouwman P, Aly A, Escandell JM, Pieterse M, Bartkova J, van der Gulden H, Hiddingh S, Thanasoula M, Kulkarni A, Yang Q, Haffty BG, Tommiska J, Blomqvist C, Drapkin R, Adams DJ, Nevanlinna H, Bartek J, Tarsounas M, Ganesan S, Jonkers J. Bouwman P, et al. Among authors: tarsounas m. Nat Struct Mol Biol. 2010 Jun;17(6):688-95. doi: 10.1038/nsmb.1831. Epub 2010 May 9. Nat Struct Mol Biol. 2010. PMID: 20453858 Free PMC article.

7

TPP1 is required for TERT recruitment, telomere elongation during nuclear reprogramming, and normal skin development in mice.

Tejera AM, Stagno d'Alcontres M, Thanasoula M, Marion RM, Martinez P, Liao C, Flores JM, Tarsounas M, Blasco MA. Tejera AM, et al. Among authors: tarsounas m. Dev Cell. 2010 May 18;18(5):775-89. doi: 10.1016/j.devcel.2010.03.011. Dev Cell. 2010. PMID: 20493811 Free PMC article.

8

BRCA2 acts as a RAD51 loader to facilitate telomere replication and capping.

Badie S, Escandell JM, Bouwman P, Carlos AR, Thanasoula M, Gallardo MM, Suram A, Jaco I, Benitez J, Herbig U, Blasco MA, Jonkers J, Tarsounas M. Badie S, et al. Among authors: tarsounas m. Nat Struct Mol Biol. 2010 Dec;17(12):1461-9. doi: 10.1038/nsmb.1943. Epub 2010 Nov 14. Nat Struct Mol Biol. 2010. PMID: 21076401 Free PMC article.

9

ATM/ATR checkpoint activation downregulates CDC25C to prevent mitotic entry with uncapped telomeres.

Thanasoula M, Escandell JM, Suwaki N, Tarsounas M. Thanasoula M, et al. Among authors: tarsounas m. EMBO J. 2012 Aug 15;31(16):3398-410. doi: 10.1038/emboj.2012.191. Epub 2012 Jul 27. EMBO J. 2012. PMID: 22842784 Free PMC article.

10

ARF triggers senescence in Brca2-deficient cells by altering the spectrum of p53 transcriptional targets.

Carlos AR, Escandell JM, Kotsantis P, Suwaki N, Bouwman P, Badie S, Folio C, Benitez J, Gomez-Lopez G, Pisano DG, Jonkers J, Tarsounas M. Carlos AR, et al. Among authors: tarsounas m. Nat Commun. 2013;4:2697. doi: 10.1038/ncomms3697. Nat Commun. 2013. PMID: 24162189 Free article.

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