Watson IR - Search Results

1

Oncolytic targeting of renal cell carcinoma via encephalomyocarditis virus.

Roos FC, Roberts AM, Hwang II, Moriyama EH, Evans AJ, Sybingco S, Watson IR, Carneiro LA, Gedye C, Girardin SE, Ailles LE, Jewett MA, Milosevic M, Wilson BC, Bell JC, Der SD, Ohh M. Roos FC, et al. Among authors: watson ir. EMBO Mol Med. 2010 Jul;2(7):275-88. doi: 10.1002/emmm.201000081. EMBO Mol Med. 2010. PMID: 20623734 Free PMC article.

2

Expression of p53 in renal carcinoma cells is independent of pVHL.

Stickle NH, Cheng LS, Watson IR, Alon N, Malkin D, Irwin MS, Ohh M. Stickle NH, et al. Among authors: watson ir. Mutat Res. 2005 Oct 15;578(1-2):23-32. doi: 10.1016/j.mrfmmm.2005.02.016. Epub 2005 Jul 5. Mutat Res. 2005. PMID: 15998523

3

Loss of VHL confers hypoxia-inducible factor (HIF)-dependent resistance to vesicular stomatitis virus: role of HIF in antiviral response.

Hwang II, Watson IR, Der SD, Ohh M. Hwang II, et al. Among authors: watson ir. J Virol. 2006 Nov;80(21):10712-23. doi: 10.1128/JVI.01014-06. Epub 2006 Aug 23. J Virol. 2006. PMID: 16928739 Free PMC article.

4

Mdm2-mediated NEDD8 modification of TAp73 regulates its transactivation function.

Watson IR, Blanch A, Lin DC, Ohh M, Irwin MS. Watson IR, et al. J Biol Chem. 2006 Nov 10;281(45):34096-103. doi: 10.1074/jbc.M603654200. Epub 2006 Sep 14. J Biol Chem. 2006. PMID: 16980297 Free article.

5

Chemotherapy induces NEDP1-mediated destabilization of MDM2.

Watson IR, Li BK, Roche O, Blanch A, Ohh M, Irwin MS. Watson IR, et al. Oncogene. 2010 Jan 14;29(2):297-304. doi: 10.1038/onc.2009.314. Epub 2009 Sep 28. Oncogene. 2010. PMID: 19784069

6

Suppression of hypoxia-inducible factor 2alpha restores p53 activity via Hdm2 and reverses chemoresistance of renal carcinoma cells.

Roberts AM, Watson IR, Evans AJ, Foster DA, Irwin MS, Ohh M. Roberts AM, et al. Among authors: watson ir. Cancer Res. 2009 Dec 1;69(23):9056-64. doi: 10.1158/0008-5472.CAN-09-1770. Epub 2009 Nov 17. Cancer Res. 2009. PMID: 19920202 Free PMC article.

7

NEDD8 pathways in cancer, Sine Quibus Non.

Watson IR, Irwin MS, Ohh M. Watson IR, et al. Cancer Cell. 2011 Feb 15;19(2):168-76. doi: 10.1016/j.ccr.2011.01.002. Cancer Cell. 2011. PMID: 21316600 Free article. Review.

8

Eukaryotic translation elongation factor 1-alpha 1 inhibits p53 and p73 dependent apoptosis and chemotherapy sensitivity.

Blanch A, Robinson F, Watson IR, Cheng LS, Irwin MS. Blanch A, et al. Among authors: watson ir. PLoS One. 2013 Jun 14;8(6):e66436. doi: 10.1371/journal.pone.0066436. Print 2013. PLoS One. 2013. PMID: 23799104 Free PMC article.

9

Mutations in the IFNγ-JAK-STAT Pathway Causing Resistance to Immune Checkpoint Inhibitors in Melanoma Increase Sensitivity to Oncolytic Virus Treatment.

Nguyen TT, Ramsay L, Ahanfeshar-Adams M, Lajoie M, Schadendorf D, Alain T, Watson IR. Nguyen TT, et al. Among authors: watson ir. Clin Cancer Res. 2021 Jun 15;27(12):3432-3442. doi: 10.1158/1078-0432.CCR-20-3365. Epub 2021 Feb 16. Clin Cancer Res. 2021. PMID: 33593882

10

Dual MAPK Inhibition Is an Effective Therapeutic Strategy for a Subset of Class II BRAF Mutant Melanomas.

Dankner M, Lajoie M, Moldoveanu D, Nguyen TT, Savage P, Rajkumar S, Huang X, Lvova M, Protopopov A, Vuzman D, Hogg D, Park M, Guiot MC, Petrecca K, Mihalcioiu C, Watson IR, Siegel PM, Rose AAN. Dankner M, et al. Among authors: watson ir. Clin Cancer Res. 2018 Dec 15;24(24):6483-6494. doi: 10.1158/1078-0432.CCR-17-3384. Epub 2018 Jun 14. Clin Cancer Res. 2018. PMID: 29903896

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