Grainger D - Search Results

1

Safety in magnetic resonance units: an update.

Association of Anaesthetists of Great Britain and Ireland; Farling PA, Flynn PA, Darwent G, De Wilde J, Grainger D, King S, McBrien ME, Menon DK, Ridgway JP, Sury M, Thornton J, Wilson SR. Association of Anaesthetists of Great Britain and Ireland, et al. Among authors: grainger d. Anaesthesia. 2010 Jul;65(7):766-70. doi: 10.1111/j.1365-2044.2010.06377.x. Anaesthesia. 2010. PMID: 20642539 Free PMC article.

2

Neuroprotection in ischemia-reperfusion injury: an antiinflammatory approach using a novel broad-spectrum chemokine inhibitor.

Beech JS, Reckless J, Mosedale DE, Grainger DJ, Williams SC, Menon DK. Beech JS, et al. Among authors: grainger dj. J Cereb Blood Flow Metab. 2001 Jun;21(6):683-9. doi: 10.1097/00004647-200106000-00006. J Cereb Blood Flow Metab. 2001. PMID: 11488537

3

The MHP36 line of murine neural stem cells expresses functional CXCR1 chemokine receptors that initiate chemotaxis in vitro.

Beech JS, Wheeler DW, Reckless J, Grant AJ, Price J, Mastroeni P, Grainger DJ, Menon DK. Beech JS, et al. J Neuroimmunol. 2007 Mar;184(1-2):198-208. doi: 10.1016/j.jneuroim.2006.12.015. Epub 2007 Feb 7. J Neuroimmunol. 2007. PMID: 17289163

4

Anaesthetic impairment of immune function is mediated via GABA(A) receptors.

Wheeler DW, Thompson AJ, Corletto F, Reckless J, Loke JC, Lapaque N, Grant AJ, Mastroeni P, Grainger DJ, Padgett CL, O'Brien JA, Miller NG, Trowsdale J, Lummis SC, Menon DK, Beech JS. Wheeler DW, et al. PLoS One. 2011 Feb 24;6(2):e17152. doi: 10.1371/journal.pone.0017152. PLoS One. 2011. PMID: 21390329 Free PMC article.

5

Broad spectrum chemokine inhibitors related to NR58-3.14.3.

Grainger DJ, Reckless J, Fox DJ. Grainger DJ, et al. Mini Rev Med Chem. 2005 Sep;5(9):825-32. doi: 10.2174/1389557054867101. Mini Rev Med Chem. 2005. PMID: 16178724 Review.

6

The pan-chemokine inhibitor NR58-3.14.3 abolishes tumour necrosis factor-alpha accumulation and leucocyte recruitment induced by lipopolysaccharide in vivo.

Reckless J, Tatalick LM, Grainger DJ. Reckless J, et al. Among authors: grainger dj. Immunology. 2001 Jun;103(2):244-54. doi: 10.1046/j.1365-2567.2001.01228.x. Immunology. 2001. PMID: 11412312 Free PMC article.

7

Design, synthesis, and preliminary pharmacological evaluation of N-acyl-3-aminoglutarimides as broad-spectrum chemokine inhibitors in vitro and anti-inflammatory agents in vivo.

Fox DJ, Reckless J, Warren SG, Grainger DJ. Fox DJ, et al. J Med Chem. 2002 Jan 17;45(2):360-70. doi: 10.1021/jm010984i. J Med Chem. 2002. PMID: 11784140

8

Broad-spectrum chemokine inhibitors (BSCIs) and their anti-inflammatory effects in vivo.

Grainger DJ, Reckless J. Grainger DJ, et al. Biochem Pharmacol. 2003 Apr 1;65(7):1027-34. doi: 10.1016/s0006-2952(02)01626-x. Biochem Pharmacol. 2003. PMID: 12663038 Review.

9

Broad-spectrum chemokine inhibition reduces vascular macrophage accumulation and collagenolysis consistent with plaque stabilization in mice.

Reckless J, Tatalick L, Wilbert S, McKilligin E, Grainger DJ. Reckless J, et al. J Vasc Res. 2005 Nov-Dec;42(6):492-502. doi: 10.1159/000088139. Epub 2005 Sep 7. J Vasc Res. 2005. PMID: 16155365

10

Highly potent, orally available anti-inflammatory broad-spectrum chemokine inhibitors.

Fox DJ, Reckless J, Lingard H, Warren S, Grainger DJ. Fox DJ, et al. J Med Chem. 2009 Jun 11;52(11):3591-5. doi: 10.1021/jm900133w. J Med Chem. 2009. PMID: 19425597

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