Ortqvist P - Search Results

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Discovery of achiral inhibitors of the hepatitis C virus NS3 protease based on 2(1H)-pyrazinones.

Ortqvist P, Gising J, Ehrenberg AE, Vema A, Borg A, Karlén A, Larhed M, Danielson UH, Sandström A. Ortqvist P, et al. Bioorg Med Chem. 2010 Sep 1;18(17):6512-25. doi: 10.1016/j.bmc.2010.06.101. Epub 2010 Jul 3. Bioorg Med Chem. 2010. PMID: 20673728

Phenylglycine as a novel P2 scaffold in hepatitis C virus NS3 protease inhibitors.

Ortqvist P, Peterson SD, Kerblom E, Gossas T, Sabnis YA, Fransson R, Lindeberg G, Helena Danielson U, Karlén A, Sandström A. Ortqvist P, et al. Bioorg Med Chem. 2007 Feb 1;15(3):1448-74. doi: 10.1016/j.bmc.2006.11.003. Epub 2006 Nov 6. Bioorg Med Chem. 2007. PMID: 17113777

A straightforward microwave method for rapid synthesis of N-1, C-6 functionalized 3,5-dichloro-2(1H)-pyrazinones.

Gising J, Ortqvist P, Sandström A, Larhed M. Gising J, et al. Among authors: ortqvist p. Org Biomol Chem. 2009 Jul 7;7(13):2809-15. doi: 10.1039/b905501k. Epub 2009 May 27. Org Biomol Chem. 2009. PMID: 19532999

Structure-activity relationships of HCV NS3 protease inhibitors evaluated on the drug-resistant variants A156T and D168V.

Ortqvist P, Vema A, Ehrenberg AE, Dahl G, Rönn R, Akerblom E, Karlén A, Danielson UH, Sandström A. Ortqvist P, et al. Antivir Ther. 2010;15(6):841-52. doi: 10.3851/IMP1655. Antivir Ther. 2010. PMID: 20834096

Treatment of hepatitis C virus infection in adults and children: updated Swedish consensus recommendations.

Lagging M, Duberg AS, Wejstål R, Weiland O, Lindh M, Aleman S, Josephson F; Swedish Consensus Group. Lagging M, et al. Scand J Infect Dis. 2012 Jul;44(7):502-21. doi: 10.3109/00365548.2012.669045. Epub 2012 Apr 16. Scand J Infect Dis. 2012. PMID: 22506634 Review.

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