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Specific loss of brain ABCA1 increases brain cholesterol uptake and influences neuronal structure and function.
Karasinska JM, Rinninger F, Lütjohann D, Ruddle P, Franciosi S, Kruit JK, Singaraja RR, Hirsch-Reinshagen V, Fan J, Brunham LR, Bissada N, Ramakrishnan R, Wellington CL, Parks JS, Hayden MR. Karasinska JM, et al. Among authors: fan j. J Neurosci. 2009 Mar 18;29(11):3579-89. doi: 10.1523/JNEUROSCI.4741-08.2009. J Neurosci. 2009. PMID: 19295162 Free PMC article.
ABCA1 influences neuroinflammation and neuronal death.
Karasinska JM, de Haan W, Franciosi S, Ruddle P, Fan J, Kruit JK, Stukas S, Lütjohann D, Gutmann DH, Wellington CL, Hayden MR. Karasinska JM, et al. Among authors: fan j. Neurobiol Dis. 2013 Jun;54:445-55. doi: 10.1016/j.nbd.2013.01.018. Epub 2013 Jan 30. Neurobiol Dis. 2013. PMID: 23376685
HDL from an Alzheimer's disease perspective.
Button EB, Robert J, Caffrey TM, Fan J, Zhao W, Wellington CL. Button EB, et al. Among authors: fan j. Curr Opin Lipidol. 2019 Jun;30(3):224-234. doi: 10.1097/MOL.0000000000000604. Curr Opin Lipidol. 2019. PMID: 30946049 Free PMC article. Review.
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