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The PD-L1/CD86 ratio is increased in dendritic cells co-infected with porcine circovirus type 2 and porcine reproductive and respiratory syndrome virus, and the PD-L1/PD-1 axis is associated with anergy, apoptosis, and the induction of regulatory T-cells in porcine lymphocytes.
Richmond O, Cecere TE, Erdogan E, Meng XJ, Piñeyro P, Subramaniam S, Todd SM, LeRoith T. Richmond O, et al. Among authors: subramaniam s. Vet Microbiol. 2015 Nov 18;180(3-4):223-9. doi: 10.1016/j.vetmic.2015.09.014. Epub 2015 Sep 21. Vet Microbiol. 2015. PMID: 26446939
PD-L1 expression is increased in monocyte derived dendritic cells in response to porcine circovirus type 2 and porcine reproductive and respiratory syndrome virus infections.
Richmond O, Cecere TE, Erdogan E, Meng XJ, Piñeyro P, Subramaniam S, Todd SM, LeRoith T. Richmond O, et al. Among authors: subramaniam s. Vet Immunol Immunopathol. 2015 Nov 15;168(1-2):24-9. doi: 10.1016/j.vetimm.2015.09.013. Epub 2015 Sep 28. Vet Immunol Immunopathol. 2015. PMID: 26553563
Dendritic cell-targeted porcine reproductive and respiratory syndrome virus (PRRSV) antigens adjuvanted with polyinosinic-polycytidylic acid (poly (I:C)) induced non-protective immune responses against heterologous type 2 PRRSV challenge in pigs.
Subramaniam S, Piñeyro P, Derscheid RJ, Madson DM, Magstadt DR, Meng XJ. Subramaniam S, et al. Vet Immunol Immunopathol. 2017 Aug;190:18-25. doi: 10.1016/j.vetimm.2017.07.003. Epub 2017 Jul 10. Vet Immunol Immunopathol. 2017. PMID: 28778318
1,569 results