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High expression of HIF1a is a predictor of clinical outcome in patients with pancreatic ductal adenocarcinomas and correlated to PDGFA, VEGF, and bFGF.
Hoffmann AC, Mori R, Vallbohmer D, Brabender J, Klein E, Drebber U, Baldus SE, Cooc J, Azuma M, Metzger R, Hoelscher AH, Danenberg KD, Prenzel KL, Danenberg PV. Hoffmann AC, et al. Among authors: drebber u. Neoplasia. 2008 Jul;10(7):674-9. doi: 10.1593/neo.08292. Neoplasia. 2008. PMID: 18592007 Free PMC article.
High expression of heparanase is significantly associated with dedifferentiation and lymph node metastasis in patients with pancreatic ductal adenocarcinomas and correlated to PDGFA and via HIF1a to HB-EGF and bFGF.
Hoffmann AC, Mori R, Vallbohmer D, Brabender J, Drebber U, Baldus SE, Klein E, Azuma M, Metzger R, Hoffmann C, Hoelscher AH, Danenberg KD, Prenzel KL, Danenberg PV. Hoffmann AC, et al. Among authors: drebber u. J Gastrointest Surg. 2008 Oct;12(10):1674-81; discussion 1681-2. doi: 10.1007/s11605-008-0628-2. Epub 2008 Aug 13. J Gastrointest Surg. 2008. PMID: 18704599
232 results