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Targeting glucosylceramide synthase upregulation reverts sorafenib resistance in experimental hepatocellular carcinoma.
Stefanovic M, Tutusaus A, Martinez-Nieto GA, Bárcena C, de Gregorio E, Moutinho C, Barbero-Camps E, Villanueva A, Colell A, Marí M, García-Ruiz C, Fernandez-Checa JC, Morales A. Stefanovic M, et al. Among authors: barcena c. Oncotarget. 2016 Feb 16;7(7):8253-67. doi: 10.18632/oncotarget.6982. Oncotarget. 2016. PMID: 26811497 Free PMC article.
CD5L is upregulated in hepatocellular carcinoma and promotes liver cancer cell proliferation and antiapoptotic responses by binding to HSPA5 (GRP78).
Aran G, Sanjurjo L, Bárcena C, Simon-Coma M, Téllez É, Vázquez-Vitali M, Garrido M, Guerra L, Díaz E, Ojanguren I, Elortza F, Planas R, Sala M, Armengol C, Sarrias MR. Aran G, et al. Among authors: barcena c. FASEB J. 2018 Jul;32(7):3878-3891. doi: 10.1096/fj.201700941RR. Epub 2018 Feb 20. FASEB J. 2018. PMID: 29465313
Furthermore, functional experiments revealed that CD5L activates the UPR and autophagy mechanisms in Huh7 cells, thereby providing a novel molecular link between the UPR and autophagy in liver cancer.-Aran, G., Sanjurjo, L., Barcena, C., Simon-Coma, M., Tellez, E., …
Furthermore, functional experiments revealed that CD5L activates the UPR and autophagy mechanisms in Huh7 cells, thereby providing a novel m …
Testicular large B-cell lymphoma is genetically similar to PCNSL and distinct from nodal DLBCL.
Rivas-Delgado A, López C, Clot G, Nadeu F, Grau M, Frigola G, Bosch-Schips J, Radke J, Ishaque N, Alcoceba M, Tapia G, Luizaga L, Barcena C, Kelleher N, Villamor N, Baumann T, Muntañola A, Sancho-Cia JM, García-Sancho AM, Gonzalez-Barca E, Matutes E, Brito JA, Karube K, Salaverria I, Enjuanes A, Wiemann S, Heppner FL, Siebert R, Climent F, Campo E, Giné E, López-Guillermo A, Beà S. Rivas-Delgado A, et al. Among authors: barcena c. Hemasphere. 2024 Oct 7;8(10):e70024. doi: 10.1002/hem3.70024. eCollection 2024 Oct. Hemasphere. 2024. PMID: 39380845 Free PMC article.
96 results