Schmitt M - Search Results

1

A pharmacokinetic-pharmacodynamic model for cardiovascular safety assessment of R1551.

Fleury A, Lavé T, Jonsson F, Schmitt M, Hirkaler G, Polonchuk L, Breidenbach A. Fleury A, et al. Among authors: schmitt m. J Pharmacol Toxicol Methods. 2011 Jan-Feb;63(1):123-33. doi: 10.1016/j.vascn.2010.08.003. Epub 2010 Aug 21. J Pharmacol Toxicol Methods. 2011. PMID: 20732434

2

Interspecies pharmacokinetic comparisons and allometric scaling of napsagatran, a low molecular weight thrombin inhibitor.

Lavé T, Portmann R, Schenker G, Gianni A, Guenzi A, Girometta MA, Schmitt M. Lavé T, et al. Among authors: schmitt m. J Pharm Pharmacol. 1999 Jan;51(1):85-91. doi: 10.1211/0022357991772006. J Pharm Pharmacol. 1999. PMID: 10197423

3

Interspecies scaling of tolcapone, a new inhibitor of catechol-O-methyltransferase (COMT). Use of in vitro data from hepatocytes to predict metabolic clearance in animals and humans.

Lave T, Dupin S, Schmitt M, Kapps M, Meyer J, Morgenroth B, Chou RC, Jaeck D, Coassolo P. Lave T, et al. Among authors: schmitt m. Xenobiotica. 1996 Aug;26(8):839-51. doi: 10.3109/00498259609046754. Xenobiotica. 1996. PMID: 8879148

4

Rational design of novel pyrrolidine derivatives as orally active neurokinin-3 receptor antagonists.

Ratni H, Ballard TM, Bissantz C, Hoffmann T, Jablonski P, Knoflach F, Knust H, Malherbe P, Nettekoven M, Patiny-Adam A, Riemer C, Schmitt M, Spooren W. Ratni H, et al. Among authors: schmitt m. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6735-8. doi: 10.1016/j.bmcl.2010.08.138. Epub 2010 Sep 17. Bioorg Med Chem Lett. 2010. PMID: 20850972

5

Pharmacokinetic-pharmacodynamic interaction between the COMT inhibitor tolcapone and single-dose levodopa.

Dingemanse J, Jorga K, Zürcher G, Schmitt M, Sedek G, Da Prada M, Van Brummelen P. Dingemanse J, et al. Among authors: schmitt m. Br J Clin Pharmacol. 1995 Sep;40(3):253-62. doi: 10.1111/j.1365-2125.1995.tb05781.x. Br J Clin Pharmacol. 1995. PMID: 8527287 Free PMC article. Clinical Trial.

6

Determination of the catechol-O-methyltransferase inhibitor tolcapone and three of its metabolites in animal and human plasma and urine by reversed-phase high-performance liquid chromatography with ultraviolet detection.

Heizmann P, Schmitt M, Leube J, Martin H, Saner A. Heizmann P, et al. Among authors: schmitt m. J Chromatogr B Biomed Sci Appl. 1999 Jul 9;730(2):153-60. doi: 10.1016/s0378-4347(99)00146-2. J Chromatogr B Biomed Sci Appl. 1999. PMID: 10448949

7

Biopharmaceutical evaluation of ketoprofen following intravenous, oral, and rectal administration in dogs.

Schmitt M, Guentert TW. Schmitt M, et al. J Pharm Sci. 1990 Jul;79(7):614-6. doi: 10.1002/jps.2600790715. J Pharm Sci. 1990. PMID: 2398469

8

Biopharmaceutical evaluation of carprofen following single intravenous, oral, and rectal doses in dogs.

Schmitt M, Guentert TW. Schmitt M, et al. Biopharm Drug Dispos. 1990 Oct;11(7):585-94. doi: 10.1002/bdd.2510110704. Biopharm Drug Dispos. 1990. PMID: 2265238

9

Integrated pharmacokinetics and pharmacodynamics of the novel catechol-O-methyltransferase inhibitor tolcapone during first administration to humans.

Dingemanse J, Jorga KM, Schmitt M, Gieschke R, Fotteler B, Zürcher G, Da Prada M, van Brummelen P. Dingemanse J, et al. Among authors: schmitt m. Clin Pharmacol Ther. 1995 May;57(5):508-17. doi: 10.1016/0009-9236(95)90035-7. Clin Pharmacol Ther. 1995. PMID: 7768073 Clinical Trial.

10

Orally active fibrinogen receptor antagonists. 2. Amidoximes as prodrugs of amidines.

Weller T, Alig L, Beresini M, Blackburn B, Bunting S, Hadváry P, Müller MH, Knopp D, Levet-Trafit B, Lipari MT, Modi NB, Müller M, Refino CJ, Schmitt M, Schönholzer P, Weiss S, Steiner B. Weller T, et al. Among authors: schmitt m. J Med Chem. 1996 Aug 2;39(16):3139-47. doi: 10.1021/jm9509298. J Med Chem. 1996. PMID: 8759635

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