Geurink PP - Search Results

1

Activity-based profiling reveals reactivity of the murine thymoproteasome-specific subunit beta5t.

Florea BI, Verdoes M, Li N, van der Linden WA, Geurink PP, van den Elst H, Hofmann T, de Ru A, van Veelen PA, Tanaka K, Sasaki K, Murata S, den Dulk H, Brouwer J, Ossendorp FA, Kisselev AF, Overkleeft HS. Florea BI, et al. Among authors: geurink pp. Chem Biol. 2010 Aug 27;17(8):795-801. doi: 10.1016/j.chembiol.2010.05.027. Chem Biol. 2010. PMID: 20797608 Free PMC article.

2

A Pro-Fluorescent Ubiquitin-Based Probe to Monitor Cysteine-Based E3 Ligase Activity.

Pérez Berrocal DA, Vishwanatha TM, Horn-Ghetko D, Botsch JJ, Hehl LA, Kostrhon S, Misra M, Ðikić I, Geurink PP, van Dam H, Schulman BA, Mulder MPC. Pérez Berrocal DA, et al. Among authors: geurink pp. Angew Chem Int Ed Engl. 2023 Aug 7;62(32):e202303319. doi: 10.1002/anie.202303319. Epub 2023 Jun 27. Angew Chem Int Ed Engl. 2023. PMID: 37272691

3

Mechanism of Lys6 poly-ubiquitin specificity by the L. pneumophila deubiquitinase LotA.

Warren GD, Kitao T, Franklin TG, Nguyen JV, Geurink PP, Kubori T, Nagai H, Pruneda JN. Warren GD, et al. Among authors: geurink pp. Mol Cell. 2023 Jan 5;83(1):105-120.e5. doi: 10.1016/j.molcel.2022.11.022. Epub 2022 Dec 19. Mol Cell. 2023. PMID: 36538933 Free PMC article.

4

Solid-phase synthesis of succinylhydroxamate peptides: functionalized matrix metalloproteinase inhibitors.

Leeuwenburgh MA, Geurink PP, Klein T, Kauffman HF, van der Marel GA, Bischoff R, Overkleeft HS. Leeuwenburgh MA, et al. Among authors: geurink pp. Org Lett. 2006 Apr 13;8(8):1705-8. doi: 10.1021/ol060409e. Org Lett. 2006. PMID: 16597146

5

A peptide hydroxamate library for enrichment of metalloproteinases: towards an affinity-based metalloproteinase profiling protocol.

Geurink P, Klein T, Leeuwenburgh M, van der Marel G, Kauffman H, Bischoff R, Overkleeft H. Geurink P, et al. Org Biomol Chem. 2008 Apr 7;6(7):1244-50. doi: 10.1039/b718352f. Epub 2008 Feb 22. Org Biomol Chem. 2008. PMID: 18362965

6

Incorporation of fluorinated phenylalanine generates highly specific inhibitor of proteasome's chymotrypsin-like sites.

Geurink PP, Liu N, Spaans MP, Downey SL, van den Nieuwendijk AM, van der Marel GA, Kisselev AF, Florea BI, Overkleeft HS. Geurink PP, et al. J Med Chem. 2010 Mar 11;53(5):2319-23. doi: 10.1021/jm9015685. J Med Chem. 2010. PMID: 20131905 Free PMC article.

7

Proteasome selectivity towards Michael acceptor containing oligopeptide-based inhibitors.

van der Linden WA, Geurink PP, Oskam C, van der Marel GA, Florea BI, Overkleeft HS. van der Linden WA, et al. Among authors: geurink pp. Org Biomol Chem. 2010 Apr 21;8(8):1885-93. doi: 10.1039/b924134e. Org Biomol Chem. 2010. PMID: 20449494

8

A cleavable linker based on the levulinoyl ester for activity-based protein profiling.

Geurink PP, Florea BI, Li N, Witte MD, Verasdonck J, Kuo CL, van der Marel GA, Overkleeft HS. Geurink PP, et al. Angew Chem Int Ed Engl. 2010 Sep 10;49(38):6802-5. doi: 10.1002/anie.201001767. Angew Chem Int Ed Engl. 2010. PMID: 20715027 No abstract available.

9

Nature of pharmacophore influences active site specificity of proteasome inhibitors.

Screen M, Britton M, Downey SL, Verdoes M, Voges MJ, Blom AE, Geurink PP, Risseeuw MD, Florea BI, van der Linden WA, Pletnev AA, Overkleeft HS, Kisselev AF. Screen M, et al. Among authors: geurink pp. J Biol Chem. 2010 Dec 17;285(51):40125-34. doi: 10.1074/jbc.M110.160606. Epub 2010 Oct 11. J Biol Chem. 2010. PMID: 20937826 Free PMC article.

10

Probing the proteasome cavity in three steps: bio-orthogonal photo-reactive suicide substrates.

Geurink PP, Florea BI, Van der Marel GA, Kessler BM, Overkleeft HS. Geurink PP, et al. Chem Commun (Camb). 2010 Dec 21;46(47):9052-4. doi: 10.1039/c0cc03322g. Epub 2010 Oct 27. Chem Commun (Camb). 2010. PMID: 20981375

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