El Sayed KA - Search Results

1

Phenylmethylene hydantoins as prostate cancer invasion and migration inhibitors. CoMFA approach and QSAR analysis.

Khanfar MA, El Sayed KA. Khanfar MA, et al. Among authors: el sayed ka. Eur J Med Chem. 2010 Nov;45(11):5397-405. doi: 10.1016/j.ejmech.2010.08.066. Epub 2010 Sep 8. Eur J Med Chem. 2010. PMID: 20869139

2

Natural products as angiogenesis modulators.

El Sayed KA. El Sayed KA. Mini Rev Med Chem. 2005 Nov;5(11):971-93. doi: 10.2174/138955705774575291. Mini Rev Med Chem. 2005. PMID: 16307528 Review.

3

Biocatalytic and semisynthetic optimization of the anti-invasive tobacco (1S,2E,4R,6R,7E,11E)-2,7,11-cembratriene-4,6-diol.

El Sayed KA, Laphookhieo S, Baraka HN, Yousaf M, Hebert A, Bagaley D, Rainey FA, Muralidharan A, Thomas S, Shah GV. El Sayed KA, et al. Bioorg Med Chem. 2008 Mar 15;16(6):2886-93. doi: 10.1016/j.bmc.2007.12.056. Epub 2008 Jan 3. Bioorg Med Chem. 2008. PMID: 18222089

4

Discovery, design, and synthesis of anti-metastatic lead phenylmethylene hydantoins inspired by marine natural products.

Mudit M, Khanfar M, Muralidharan A, Thomas S, Shah GV, van Soest RW, El Sayed KA. Mudit M, et al. Among authors: el sayed ka. Bioorg Med Chem. 2009 Feb 15;17(4):1731-8. doi: 10.1016/j.bmc.2008.12.053. Epub 2008 Dec 29. Bioorg Med Chem. 2009. PMID: 19195897

5

Identification of a small molecule class to enhance cell-cell adhesion and attenuate prostate tumor growth and metastasis.

Shah GV, Muralidharan A, Thomas S, Gokulgandhi M, Mudit M, Khanfar M, El Sayed K. Shah GV, et al. Mol Cancer Ther. 2009 Mar;8(3):509-20. doi: 10.1158/1535-7163.MCT-08-0693. Epub 2009 Mar 10. Mol Cancer Ther. 2009. PMID: 19276166 Free PMC article.

6

The marine natural-derived inhibitors of glycogen synthase kinase-3beta phenylmethylene hydantoins: In vitro and in vivo activities and pharmacophore modeling.

Khanfar MA, Asal BA, Mudit M, Kaddoumi A, El Sayed KA. Khanfar MA, et al. Among authors: el sayed ka. Bioorg Med Chem. 2009 Aug 15;17(16):6032-9. doi: 10.1016/j.bmc.2009.06.054. Epub 2009 Jun 27. Bioorg Med Chem. 2009. PMID: 19616957 Free PMC article.

7

Rational design and semisynthesis of betulinic acid analogues as potent topoisomerase inhibitors.

Bar FM, Khanfar MA, Elnagar AY, Liu H, Zaghloul AM, Badria FA, Sylvester PW, Ahmad KF, Raisch KP, El Sayed KA. Bar FM, et al. Among authors: el sayed ka. J Nat Prod. 2009 Sep;72(9):1643-50. doi: 10.1021/np900312u. J Nat Prod. 2009. PMID: 19691293

8

Design and preliminary structure-activity relationship of redox-silent semisynthetic tocotrienol analogues as inhibitors for breast cancer proliferation and invasion.

Elnagar AY, Wali VB, Sylvester PW, El Sayed KA. Elnagar AY, et al. Among authors: el sayed ka. Bioorg Med Chem. 2010 Jan 15;18(2):755-68. doi: 10.1016/j.bmc.2009.11.054. Epub 2009 Nov 27. Bioorg Med Chem. 2010. PMID: 20022507

9

Design and pharmacophore modeling of biaryl methyl eugenol analogs as breast cancer invasion inhibitors.

Abdel Bar FM, Khanfar MA, Elnagar AY, Badria FA, Zaghloul AM, Ahmad KF, Sylvester PW, El Sayed KA. Abdel Bar FM, et al. Among authors: el sayed ka. Bioorg Med Chem. 2010 Jan 15;18(2):496-507. doi: 10.1016/j.bmc.2009.12.019. Epub 2009 Dec 11. Bioorg Med Chem. 2010. PMID: 20034800

10

Semisynthetic latrunculin derivatives as inhibitors of metastatic breast cancer: biological evaluations, preliminary structure-activity relationship and molecular modeling studies.

Khanfar MA, Youssef DT, El Sayed KA. Khanfar MA, et al. Among authors: el sayed ka. ChemMedChem. 2010 Feb 1;5(2):274-85. doi: 10.1002/cmdc.200900430. ChemMedChem. 2010. PMID: 20043312 Free PMC article.

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