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Elicitation of structure-specific antibodies by epitope scaffolds.
Ofek G, Guenaga FJ, Schief WR, Skinner J, Baker D, Wyatt R, Kwong PD. Ofek G, et al. Among authors: schief wr. Proc Natl Acad Sci U S A. 2010 Oct 19;107(42):17880-7. doi: 10.1073/pnas.1004728107. Epub 2010 Sep 27. Proc Natl Acad Sci U S A. 2010. PMID: 20876137 Free PMC article.
DeGlyPHER: Highly sensitive site-specific analysis of N-linked glycans on proteins.
Baboo S, Diedrich JK, Martínez-Bartolomé S, Wang X, Schiffner T, Groschel B, Schief WR, Paulson JC, Yates JR 3rd. Baboo S, et al. Among authors: schief wr. Methods Enzymol. 2023;682:137-185. doi: 10.1016/bs.mie.2022.09.004. Epub 2022 Dec 26. Methods Enzymol. 2023. PMID: 36948700 Free PMC article.
Author Correction: Long-primed germinal centres with enduring affinity maturation and clonal migration.
Lee JH, Sutton HJ, Cottrell CA, Phung I, Ozorowski G, Sewall LM, Nedellec R, Nakao C, Silva M, Richey ST, Torres JL, Lee WH, Georgeson E, Kubitz M, Hodges S, Mullen TM, Adachi Y, Cirelli KM, Kaur A, Allers C, Fahlberg M, Grasperge BF, Dufour JP, Schiro F, Aye PP, Kalyuzhniy O, Liguori A, Carnathan DG, Silvestri G, Shen X, Montefiori DC, Veazey RS, Ward AB, Hangartner L, Burton DR, Irvine DJ, Schief WR, Crotty S. Lee JH, et al. Among authors: schief wr. Nature. 2023 Feb;614(7949):E43. doi: 10.1038/s41586-023-05741-1. Nature. 2023. PMID: 36717721 Free PMC article. No abstract available.
Low protease activity in B cell follicles promotes retention of intact antigens after immunization.
Aung A, Cui A, Maiorino L, Amini AP, Gregory JR, Bukenya M, Zhang Y, Lee H, Cottrell CA, Morgan DM, Silva M, Suh H, Kirkpatrick JD, Amlashi P, Remba T, Froehle LM, Xiao S, Abraham W, Adams J, Love JC, Huyett P, Kwon DS, Hacohen N, Schief WR, Bhatia SN, Irvine DJ. Aung A, et al. Among authors: schief wr. Science. 2023 Jan 27;379(6630):eabn8934. doi: 10.1126/science.abn8934. Epub 2023 Jan 27. Science. 2023. PMID: 36701450 Free PMC article.
Immunogenicity of HIV-1 envelope glycoprotein oligomers.
Forsell MN, Schief WR, Wyatt RT. Forsell MN, et al. Among authors: schief wr. Curr Opin HIV AIDS. 2009 Sep;4(5):380-7. doi: 10.1097/COH.0b013e32832edc19. Curr Opin HIV AIDS. 2009. PMID: 20048701 Review.
Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility.
Pancera M, Majeed S, Ban YE, Chen L, Huang CC, Kong L, Kwon YD, Stuckey J, Zhou T, Robinson JE, Schief WR, Sodroski J, Wyatt R, Kwong PD. Pancera M, et al. Among authors: schief wr. Proc Natl Acad Sci U S A. 2010 Jan 19;107(3):1166-71. doi: 10.1073/pnas.0911004107. Epub 2009 Dec 28. Proc Natl Acad Sci U S A. 2010. PMID: 20080564 Free PMC article.
Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1.
Wu X, Yang ZY, Li Y, Hogerkorp CM, Schief WR, Seaman MS, Zhou T, Schmidt SD, Wu L, Xu L, Longo NS, McKee K, O'Dell S, Louder MK, Wycuff DL, Feng Y, Nason M, Doria-Rose N, Connors M, Kwong PD, Roederer M, Wyatt RT, Nabel GJ, Mascola JR. Wu X, et al. Among authors: schief wr. Science. 2010 Aug 13;329(5993):856-61. doi: 10.1126/science.1187659. Epub 2010 Jul 8. Science. 2010. PMID: 20616233 Free PMC article.
Computational design of epitope-scaffolds allows induction of antibodies specific for a poorly immunogenic HIV vaccine epitope.
Correia BE, Ban YE, Holmes MA, Xu H, Ellingson K, Kraft Z, Carrico C, Boni E, Sather DN, Zenobia C, Burke KY, Bradley-Hewitt T, Bruhn-Johannsen JF, Kalyuzhniy O, Baker D, Strong RK, Stamatatos L, Schief WR. Correia BE, et al. Among authors: schief wr. Structure. 2010 Sep 8;18(9):1116-26. doi: 10.1016/j.str.2010.06.010. Structure. 2010. PMID: 20826338 Free article.
159 results