Palatini P - Search Results

1

Flavonoids diosmetin and hesperetin are potent inhibitors of cytochrome P450 2C9-mediated drug metabolism in vitro.

Quintieri L, Bortolozzo S, Stragliotto S, Moro S, Pavanetto M, Nassi A, Palatini P, Floreani M. Quintieri L, et al. Among authors: palatini p. Drug Metab Pharmacokinet. 2010;25(5):466-76. doi: 10.2133/dmpk.dmpk-10-rg-044. Epub 2010 Sep 22. Drug Metab Pharmacokinet. 2010. PMID: 20877134 Free article.

2

Flavonoids diosmetin and luteolin inhibit midazolam metabolism by human liver microsomes and recombinant CYP 3A4 and CYP3A5 enzymes.

Quintieri L, Palatini P, Nassi A, Ruzza P, Floreani M. Quintieri L, et al. Among authors: palatini p. Biochem Pharmacol. 2008 Mar 15;75(6):1426-37. doi: 10.1016/j.bcp.2007.11.012. Epub 2007 Dec 4. Biochem Pharmacol. 2008. PMID: 18191104

3

Inhibition of cytochrome P450 2C8-mediated drug metabolism by the flavonoid diosmetin.

Quintieri L, Palatini P, Moro S, Floreani M. Quintieri L, et al. Among authors: palatini p. Drug Metab Pharmacokinet. 2011;26(6):559-68. doi: 10.2133/dmpk.DMPK-11-RG-048. Epub 2011 Jul 26. Drug Metab Pharmacokinet. 2011. PMID: 21791871 Free article.

4

Differential inducing effect of benzo[a]pyrene on gene expression and enzyme activity of cytochromes P450 1A1 and 1A2 in Sprague-Dawley and Wistar rats.

Floreani M, Gabbia D, Barbierato M, DE Martin S, Palatini P. Floreani M, et al. Among authors: palatini p. Drug Metab Pharmacokinet. 2012;27(6):640-52. doi: 10.2133/dmpk.dmpk-12-rg-035. Epub 2012 Jun 12. Drug Metab Pharmacokinet. 2012. PMID: 22785257 Free article.

5

In vitro hepatic conversion of the anticancer agent nemorubicin to its active metabolite PNU-159682 in mice, rats and dogs: a comparison with human liver microsomes.

Quintieri L, Fantin M, Palatini P, De Martin S, Rosato A, Caruso M, Geroni C, Floreani M. Quintieri L, et al. Among authors: palatini p. Biochem Pharmacol. 2008 Sep 15;76(6):784-95. doi: 10.1016/j.bcp.2008.07.003. Epub 2008 Jul 11. Biochem Pharmacol. 2008. PMID: 18671948

6

Severe liver cirrhosis markedly reduces AhR-mediated induction of cytochrome P450 in rats by decreasing the transcription of target genes.

Floreani M, De Martin S, Gabbia D, Barbierato M, Nassi A, Mescoli C, Orlando R, Bova S, Angeli P, Gola E, Sticca A, Palatini P. Floreani M, et al. Among authors: palatini p. PLoS One. 2013 Apr 23;8(4):e61983. doi: 10.1371/journal.pone.0061983. Print 2013. PLoS One. 2013. PMID: 23626760 Free PMC article.

7

Oral administration of trans-resveratrol to guinea pigs increases cardiac DT-diaphorase and catalase activities, and protects isolated atria from menadione toxicity.

Floreani M, Napoli E, Quintieri L, Palatini P. Floreani M, et al. Among authors: palatini p. Life Sci. 2003 May 2;72(24):2741-50. doi: 10.1016/s0024-3205(03)00179-6. Life Sci. 2003. PMID: 12679191

8

Irreversible CYP3A inhibition accompanied by plasma protein-binding displacement: a comparative analysis in subjects with normal and impaired liver function.

Orlando R, De Martin S, Pegoraro P, Quintieri L, Palatini P. Orlando R, et al. Among authors: palatini p. Clin Pharmacol Ther. 2009 Mar;85(3):319-26. doi: 10.1038/clpt.2008.216. Epub 2008 Nov 19. Clin Pharmacol Ther. 2009. PMID: 19020496 Clinical Trial.

9

Role of antioxidant defences in the species-specific response of isolated atria to menadione.

Floreani M, Napoli E, Palatini P. Floreani M, et al. Among authors: palatini p. Comp Biochem Physiol C Toxicol Pharmacol. 2002 Jun;132(2):143-51. doi: 10.1016/s1532-0456(02)00060-1. Comp Biochem Physiol C Toxicol Pharmacol. 2002. PMID: 12106891

10

Cytochrome P450 1A2 is a major determinant of lidocaine metabolism in vivo: effects of liver function.

Orlando R, Piccoli P, De Martin S, Padrini R, Floreani M, Palatini P. Orlando R, et al. Among authors: palatini p. Clin Pharmacol Ther. 2004 Jan;75(1):80-8. doi: 10.1016/j.clpt.2003.09.007. Clin Pharmacol Ther. 2004. PMID: 14749694 Clinical Trial.

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