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Methylation tolerance due to an O6-methylguanine DNA methyltransferase (MGMT) field defect in the colonic mucosa: an initiating step in the development of mismatch repair-deficient colorectal cancers.
Svrcek M, Buhard O, Colas C, Coulet F, Dumont S, Massaoudi I, Lamri A, Hamelin R, Cosnes J, Oliveira C, Seruca R, Gaub MP, Legrain M, Collura A, Lascols O, Tiret E, Fléjou JF, Duval A. Svrcek M, et al. Among authors: flejou jf. Gut. 2010 Nov;59(11):1516-26. doi: 10.1136/gut.2009.194787. Gut. 2010. PMID: 20947886
Screening for Lynch syndrome in colorectal cancer: are we doing enough?
Canard G, Lefevre JH, Colas C, Coulet F, Svrcek M, Lascols O, Hamelin R, Shields C, Duval A, Fléjou JF, Soubrier F, Tiret E, Parc Y. Canard G, et al. Among authors: flejou jf. Ann Surg Oncol. 2012 Mar;19(3):809-16. doi: 10.1245/s10434-011-2014-7. Epub 2011 Aug 31. Ann Surg Oncol. 2012. PMID: 21879275
Lynch or not Lynch? Is that always a question?
Colas C, Coulet F, Svrcek M, Collura A, Fléjou JF, Duval A, Hamelin R. Colas C, et al. Among authors: flejou jf. Adv Cancer Res. 2012;113:121-66. doi: 10.1016/B978-0-12-394280-7.00004-X. Adv Cancer Res. 2012. PMID: 22429854 Review.
Diagnosis of Constitutional Mismatch Repair-Deficiency Syndrome Based on Microsatellite Instability and Lymphocyte Tolerance to Methylating Agents.
Bodo S, Colas C, Buhard O, Collura A, Tinat J, Lavoine N, Guilloux A, Chalastanis A, Lafitte P, Coulet F, Buisine MP, Ilencikova D, Ruiz-Ponte C, Kinzel M, Grandjouan S, Brems H, Lejeune S, Blanché H, Wang Q, Caron O, Cabaret O, Svrcek M, Vidaud D, Parfait B, Verloes A, Knappe UJ, Soubrier F, Mortemousque I, Leis A, Auclair-Perrossier J, Frébourg T, Fléjou JF, Entz-Werle N, Leclerc J, Malka D, Cohen-Haguenauer O, Goldberg Y, Gerdes AM, Fedhila F, Mathieu-Dramard M, Hamelin R, Wafaa B, Gauthier-Villars M, Bourdeaut F, Sheridan E, Vasen H, Brugières L, Wimmer K, Muleris M, Duval A; European Consortium “Care for CMMRD”. Bodo S, et al. Among authors: flejou jf. Gastroenterology. 2015 Oct;149(4):1017-29.e3. doi: 10.1053/j.gastro.2015.06.013. Epub 2015 Jun 25. Gastroenterology. 2015. PMID: 26116798 Free article.
Specific clinical and biological features characterize inflammatory bowel disease associated colorectal cancers showing microsatellite instability.
Svrcek M, El-Bchiri J, Chalastanis A, Capel E, Dumont S, Buhard O, Oliveira C, Seruca R, Bossard C, Mosnier JF, Berger F, Leteurtre E, Lavergne-Slove A, Chenard MP, Hamelin R, Cosnes J, Beaugerie L, Tiret E, Duval A, Fléjou JF. Svrcek M, et al. Among authors: flejou jf. J Clin Oncol. 2007 Sep 20;25(27):4231-8. doi: 10.1200/JCO.2007.10.9744. J Clin Oncol. 2007. PMID: 17878476
[Clinical and molecular consequences of microsatellite instability in human cancers].
Hamelin R, Chalastanis A, Colas C, El Bchiri J, Mercier D, Schreurs AS, Simon V, Svrcek M, Zaanan A, Borie C, Buhard O, Capel E, Zouali H, Praz F, Muleris M, Fléjou JF, Duval A. Hamelin R, et al. Among authors: flejou jf. Bull Cancer. 2008 Jan;95(1):121-32. doi: 10.1684/bdc.2008.0571. Bull Cancer. 2008. PMID: 18230578 Review. French.
The mechanisms underlying MMR deficiency in immunodeficiency-related non-Hodgkin lymphomas are different from those in other sporadic microsatellite instable neoplasms.
Borie C, Colas C, Dartigues P, Lazure T, Rince P, Buhard O, Folliot P, Chalastanis A, Muleris M, Hamelin R, Mercier D, Oliveira C, Seruca R, Chadburn A, Leblond V, Barete S, Gaïdano G, Martin A, Gaulard P, Fléjou JF, Raphael M, Duval A. Borie C, et al. Among authors: flejou jf. Int J Cancer. 2009 Nov 15;125(10):2360-6. doi: 10.1002/ijc.24681. Int J Cancer. 2009. PMID: 19551857
487 results