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Page 1
Recognition of Smac-mimetic compounds by the BIR domain of cIAP1.
Cossu F, Malvezzi F, Canevari G, Mastrangelo E, Lecis D, Delia D, Seneci P, Scolastico C, Bolognesi M, Milani M. Cossu F, et al. Among authors: scolastico c. Protein Sci. 2010 Dec;19(12):2418-29. doi: 10.1002/pro.523. Protein Sci. 2010. PMID: 20954235 Free PMC article.
Targeting the X-linked inhibitor of apoptosis protein through 4-substituted azabicyclo[5.3.0]alkane smac mimetics. Structure, activity, and recognition principles.
Mastrangelo E, Cossu F, Milani M, Sorrentino G, Lecis D, Delia D, Manzoni L, Drago C, Seneci P, Scolastico C, Rizzo V, Bolognesi M. Mastrangelo E, et al. Among authors: scolastico c. J Mol Biol. 2008 Dec 19;384(3):673-89. doi: 10.1016/j.jmb.2008.09.064. Epub 2008 Oct 7. J Mol Biol. 2008. PMID: 18851976
Designing Smac-mimetics as antagonists of XIAP, cIAP1, and cIAP2.
Cossu F, Mastrangelo E, Milani M, Sorrentino G, Lecis D, Delia D, Manzoni L, Seneci P, Scolastico C, Bolognesi M. Cossu F, et al. Among authors: scolastico c. Biochem Biophys Res Commun. 2009 Jan 9;378(2):162-7. doi: 10.1016/j.bbrc.2008.10.139. Epub 2008 Nov 4. Biochem Biophys Res Commun. 2009. PMID: 18992220
Structural basis for bivalent Smac-mimetics recognition in the IAP protein family.
Cossu F, Milani M, Mastrangelo E, Vachette P, Servida F, Lecis D, Canevari G, Delia D, Drago C, Rizzo V, Manzoni L, Seneci P, Scolastico C, Bolognesi M. Cossu F, et al. Among authors: scolastico c. J Mol Biol. 2009 Sep 25;392(3):630-44. doi: 10.1016/j.jmb.2009.04.033. Epub 2009 Apr 22. J Mol Biol. 2009. PMID: 19393243
Rational design, synthesis and characterization of potent, non-peptidic Smac mimics/XIAP inhibitors as proapoptotic agents for cancer therapy.
Seneci P, Bianchi A, Battaglia C, Belvisi L, Bolognesi M, Caprini A, Cossu F, Franco Ed, Matteo Md, Delia D, Drago C, Khaled A, Lecis D, Manzoni L, Marizzoni M, Mastrangelo E, Milani M, Motto I, Moroni E, Potenza D, Rizzo V, Servida F, Turlizzi E, Varrone M, Vasile F, Scolastico C. Seneci P, et al. Among authors: scolastico c. Bioorg Med Chem. 2009 Aug 15;17(16):5834-56. doi: 10.1016/j.bmc.2009.07.009. Epub 2009 Jul 10. Bioorg Med Chem. 2009. PMID: 19620011
Dimeric Smac mimetics/IAP inhibitors as in vivo-active pro-apoptotic agents. Part II: Structural and biological characterization.
Lecis D, Mastrangelo E, Belvisi L, Bolognesi M, Civera M, Cossu F, De Cesare M, Delia D, Drago C, Manenti G, Manzoni L, Milani M, Moroni E, Perego P, Potenza D, Rizzo V, Scavullo C, Scolastico C, Servida F, Vasile F, Seneci P. Lecis D, et al. Among authors: scolastico c. Bioorg Med Chem. 2012 Nov 15;20(22):6709-23. doi: 10.1016/j.bmc.2012.09.041. Epub 2012 Sep 24. Bioorg Med Chem. 2012. PMID: 23062821
Homo- and heterodimeric Smac mimetics/IAP inhibitors as in vivo-active pro-apoptotic agents. Part I: Synthesis.
Manzoni L, Belvisi L, Bianchi A, Conti A, Drago C, de Matteo M, Ferrante L, Mastrangelo E, Perego P, Potenza D, Scolastico C, Servida F, Timpano G, Vasile F, Rizzo V, Seneci P. Manzoni L, et al. Among authors: scolastico c. Bioorg Med Chem. 2012 Nov 15;20(22):6687-708. doi: 10.1016/j.bmc.2012.09.020. Epub 2012 Sep 21. Bioorg Med Chem. 2012. PMID: 23036335
Design, synthesis, and biological evaluation of novel cRGD-paclitaxel conjugates for integrin-assisted drug delivery.
Pilkington-Miksa M, Arosio D, Battistini L, Belvisi L, De Matteo M, Vasile F, Burreddu P, Carta P, Rassu G, Perego P, Carenini N, Zunino F, De Cesare M, Castiglioni V, Scanziani E, Scolastico C, Casiraghi G, Zanardi F, Manzoni L. Pilkington-Miksa M, et al. Among authors: scolastico c. Bioconjug Chem. 2012 Aug 15;23(8):1610-22. doi: 10.1021/bc300164t. Epub 2012 Jul 20. Bioconjug Chem. 2012. PMID: 22770429
76 results