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Primary cilia regulate mTORC1 activity and cell size through Lkb1.
Boehlke C, Kotsis F, Patel V, Braeg S, Voelker H, Bredt S, Beyer T, Janusch H, Hamann C, Gödel M, Müller K, Herbst M, Hornung M, Doerken M, Köttgen M, Nitschke R, Igarashi P, Walz G, Kuehn EW. Boehlke C, et al. Among authors: igarashi p. Nat Cell Biol. 2010 Nov;12(11):1115-22. doi: 10.1038/ncb2117. Epub 2010 Oct 24. Nat Cell Biol. 2010. PMID: 20972424 Free PMC article.
HNF-1beta regulates transcription of the PKD modifier gene Kif12.
Gong Y, Ma Z, Patel V, Fischer E, Hiesberger T, Pontoglio M, Igarashi P. Gong Y, et al. Among authors: igarashi p. J Am Soc Nephrol. 2009 Jan;20(1):41-7. doi: 10.1681/ASN.2008020238. Epub 2008 Nov 12. J Am Soc Nephrol. 2009. PMID: 19005009 Free PMC article.
Loss of oriented cell division does not initiate cyst formation.
Nishio S, Tian X, Gallagher AR, Yu Z, Patel V, Igarashi P, Somlo S. Nishio S, et al. Among authors: igarashi p. J Am Soc Nephrol. 2010 Feb;21(2):295-302. doi: 10.1681/ASN.2009060603. Epub 2009 Dec 3. J Am Soc Nephrol. 2010. PMID: 19959710 Free PMC article.
MicroRNAs regulate renal tubule maturation through modulation of Pkd1.
Patel V, Hajarnis S, Williams D, Hunter R, Huynh D, Igarashi P. Patel V, et al. Among authors: igarashi p. J Am Soc Nephrol. 2012 Dec;23(12):1941-8. doi: 10.1681/ASN.2012030321. Epub 2012 Nov 8. J Am Soc Nephrol. 2012. PMID: 23138483 Free PMC article.
miR-17~92 miRNA cluster promotes kidney cyst growth in polycystic kidney disease.
Patel V, Williams D, Hajarnis S, Hunter R, Pontoglio M, Somlo S, Igarashi P. Patel V, et al. Among authors: igarashi p. Proc Natl Acad Sci U S A. 2013 Jun 25;110(26):10765-70. doi: 10.1073/pnas.1301693110. Epub 2013 Jun 12. Proc Natl Acad Sci U S A. 2013. PMID: 23759744 Free PMC article.
119 results