Machida K - Search Results

1

Hepatitis C virus inhibits DNA damage repair through reactive oxygen and nitrogen species and by interfering with the ATM-NBS1/Mre11/Rad50 DNA repair pathway in monocytes and hepatocytes.

Machida K, McNamara G, Cheng KT, Huang J, Wang CH, Comai L, Ou JH, Lai MM. Machida K, et al. J Immunol. 2010 Dec 1;185(11):6985-98. doi: 10.4049/jimmunol.1000618. Epub 2010 Oct 25. J Immunol. 2010. PMID: 20974981 Free PMC article.

2

Hepatitis C virus induces a mutator phenotype: enhanced mutations of immunoglobulin and protooncogenes.

Machida K, Cheng KT, Sung VM, Shimodaira S, Lindsay KL, Levine AM, Lai MY, Lai MM. Machida K, et al. Proc Natl Acad Sci U S A. 2004 Mar 23;101(12):4262-7. doi: 10.1073/pnas.0303971101. Epub 2004 Mar 3. Proc Natl Acad Sci U S A. 2004. PMID: 14999097 Free PMC article.

3

Hepatitis C virus infection activates the immunologic (type II) isoform of nitric oxide synthase and thereby enhances DNA damage and mutations of cellular genes.

Machida K, Cheng KT, Sung VM, Lee KJ, Levine AM, Lai MM. Machida K, et al. J Virol. 2004 Aug;78(16):8835-43. doi: 10.1128/JVI.78.16.8835-8843.2004. J Virol. 2004. PMID: 15280491 Free PMC article.

4

Hepatitis C virus E2-CD81 interaction induces hypermutation of the immunoglobulin gene in B cells.

Machida K, Cheng KT, Pavio N, Sung VM, Lai MM. Machida K, et al. J Virol. 2005 Jul;79(13):8079-89. doi: 10.1128/JVI.79.13.8079-8089.2005. J Virol. 2005. PMID: 15956553 Free PMC article.

5

Hepatitis C virus induces toll-like receptor 4 expression, leading to enhanced production of beta interferon and interleukin-6.

Machida K, Cheng KT, Sung VM, Levine AM, Foung S, Lai MM. Machida K, et al. J Virol. 2006 Jan;80(2):866-74. doi: 10.1128/JVI.80.2.866-874.2006. J Virol. 2006. PMID: 16378988 Free PMC article.

6

Hepatitis C virus triggers mitochondrial permeability transition with production of reactive oxygen species, leading to DNA damage and STAT3 activation.

Machida K, Cheng KT, Lai CK, Jeng KS, Sung VM, Lai MM. Machida K, et al. J Virol. 2006 Jul;80(14):7199-207. doi: 10.1128/JVI.00321-06. J Virol. 2006. PMID: 16809325 Free PMC article.

7

HCV core expression in hepatocytes protects against autoimmune liver injury and promotes liver regeneration in mice.

Kawamura H, Govindarajan S, Aswad F, Machida K, Lai MM, Sung VM, Dennert G. Kawamura H, et al. Among authors: machida k. Hepatology. 2006 Oct;44(4):936-44. doi: 10.1002/hep.21360. Hepatology. 2006. PMID: 17006910

8

Hepatitis C virus infects T cells and affects interferon-gamma signaling in T cell lines.

Kondo Y, Sung VM, Machida K, Liu M, Lai MM. Kondo Y, et al. Among authors: machida k. Virology. 2007 Apr 25;361(1):161-73. doi: 10.1016/j.virol.2006.11.009. Epub 2006 Dec 18. Virology. 2007. PMID: 17175001 Free article.

9

Hepatitis C virus NS3/4A protein interacts with ATM, impairs DNA repair and enhances sensitivity to ionizing radiation.

Lai CK, Jeng KS, Machida K, Cheng YS, Lai MM. Lai CK, et al. Among authors: machida k. Virology. 2008 Jan 20;370(2):295-309. doi: 10.1016/j.virol.2007.08.037. Epub 2007 Oct 10. Virology. 2008. PMID: 17931678 Free article.

10

Therapeutic control of hepatitis C virus: the role of neutralizing monoclonal antibodies.

Keck ZY, Machida K, Lai MM, Ball JK, Patel AH, Foung SK. Keck ZY, et al. Among authors: machida k. Curr Top Microbiol Immunol. 2008;317:1-38. doi: 10.1007/978-3-540-72146-8_1. Curr Top Microbiol Immunol. 2008. PMID: 17990788 Review.

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