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The cyclin E regulator cullin 3 prevents mouse hepatic progenitor cells from becoming tumor-initiating cells.
Kossatz U, Breuhahn K, Wolf B, Hardtke-Wolenski M, Wilkens L, Steinemann D, Singer S, Brass F, Kubicka S, Schlegelberger B, Schirmacher P, Manns MP, Singer JD, Malek NP. Kossatz U, et al. Among authors: wilkens l. J Clin Invest. 2010 Nov;120(11):3820-33. doi: 10.1172/JCI41959. Epub 2010 Oct 11. J Clin Invest. 2010. PMID: 20978349 Free PMC article.
Testing the importance of p27 degradation by the SCFskp2 pathway in murine models of lung and colon cancer.
Timmerbeul I, Garrett-Engele CM, Kossatz U, Chen X, Firpo E, Grünwald V, Kamino K, Wilkens L, Lehmann U, Buer J, Geffers R, Kubicka S, Manns MP, Porter PL, Roberts JM, Malek NP. Timmerbeul I, et al. Among authors: wilkens l. Proc Natl Acad Sci U S A. 2006 Sep 19;103(38):14009-14. doi: 10.1073/pnas.0606316103. Epub 2006 Sep 11. Proc Natl Acad Sci U S A. 2006. PMID: 16966613 Free PMC article.
A critical role for notch signaling in the formation of cholangiocellular carcinomas.
Zender S, Nickeleit I, Wuestefeld T, Sörensen I, Dauch D, Bozko P, El-Khatib M, Geffers R, Bektas H, Manns MP, Gossler A, Wilkens L, Plentz R, Zender L, Malek NP. Zender S, et al. Among authors: wilkens l. Cancer Cell. 2013 Jun 10;23(6):784-95. doi: 10.1016/j.ccr.2013.04.019. Epub 2013 May 30. Cancer Cell. 2013. PMID: 23727022 Free article.
Assessment of differentiation and progression of hepatic tumors using array-based comparative genomic hybridization.
Steinemann D, Skawran B, Becker T, Tauscher M, Weigmann A, Wingen L, Tauscher S, Hinrichsen T, Hertz S, Flemming P, Flik J, Wiese B, Kreipe H, Lichter P, Schlegelberger B, Wilkens L. Steinemann D, et al. Among authors: wilkens l. Clin Gastroenterol Hepatol. 2006 Oct;4(10):1283-91. doi: 10.1016/j.cgh.2006.07.010. Epub 2006 Sep 18. Clin Gastroenterol Hepatol. 2006. PMID: 16979954
880 results