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Page 1
Delayed elimination of SN-38 in cancer patients with severe renal failure.
Fujita K, Sunakawa Y, Miwa K, Akiyama Y, Sugiyama M, Kawara K, Ishida H, Yamashita K, Mizuno K, Saji S, Ichikawa W, Yamamoto W, Nagashima F, Miya T, Narabayashi M, Ando Y, Hirose T, Sasaki Y. Fujita K, et al. Among authors: miya t. Drug Metab Dispos. 2011 Feb;39(2):161-4. doi: 10.1124/dmd.110.035451. Epub 2010 Oct 27. Drug Metab Dispos. 2011. PMID: 20980446 Clinical Trial.
Gefitinib (Iressa) inhibits the CYP3A4-mediated formation of 7-ethyl-10-(4-amino-1-piperidino)carbonyloxycamptothecin but activates that of 7-ethyl-10-[4-N-(5-aminopentanoic acid)-1-piperidino]carbonyloxycamptothecin from irinotecan.
Fujita K, Ando Y, Narabayashi M, Miya T, Nagashima F, Yamamoto W, Kodama K, Araki K, Endo H, Sasaki Y. Fujita K, et al. Among authors: miya t. Drug Metab Dispos. 2005 Dec;33(12):1785-90. doi: 10.1124/dmd.105.006205. Epub 2005 Aug 25. Drug Metab Dispos. 2005. PMID: 16123050
Novel single nucleotide polymorphism of UGT1A7 gene in Japanese.
Fujita K, Ando Y, Nagashima F, Yamamoto W, Endo H, Kodama K, Araki K, Miya T, Narabayashi M, Sasaki Y. Fujita K, et al. Among authors: miya t. Drug Metab Pharmacokinet. 2006 Feb;21(1):75-8. doi: 10.2133/dmpk.21.75. Drug Metab Pharmacokinet. 2006. PMID: 16547397 Free article.
Novel single nucleotide polymorphism of UGT1A9 gene in Japanese.
Fujita K, Ando Y, Nagashima F, Yamamoto W, Endo H, Kodama K, Araki K, Miya T, Narabayashi M, Sasaki Y. Fujita K, et al. Among authors: miya t. Drug Metab Pharmacokinet. 2006 Feb;21(1):79-81. doi: 10.2133/dmpk.21.79. Drug Metab Pharmacokinet. 2006. PMID: 16547398 Free article.
Association of ATP-binding cassette, sub-family C, number 2 (ABCC2) genotype with pharmacokinetics of irinotecan in Japanese patients with metastatic colorectal cancer treated with irinotecan plus infusional 5-fluorouracil/leucovorin (FOLFIRI).
Fujita K, Nagashima F, Yamamoto W, Endo H, Sunakawa Y, Yamashita K, Ishida H, Mizuno K, Matsunaga M, Araki K, Tanaka R, Ichikawa W, Miya T, Narabayashi M, Akiyama Y, Kawara K, Ando Y, Sasaki Y. Fujita K, et al. Among authors: miya t. Biol Pharm Bull. 2008 Nov;31(11):2137-42. doi: 10.1248/bpb.31.2137. Biol Pharm Bull. 2008. PMID: 18981587 Free article. Clinical Trial.
UGT1A1*1/*28 and *1/*6 genotypes have no effects on the efficacy and toxicity of FOLFIRI in Japanese patients with advanced colorectal cancer.
Sunakawa Y, Ichikawa W, Fujita K, Nagashima F, Ishida H, Yamashita K, Mizuno K, Miwa K, Kawara K, Akiyama Y, Araki K, Yamamoto W, Miya T, Narabayashi M, Ando Y, Hirose T, Saji S, Sasaki Y. Sunakawa Y, et al. Among authors: miya t. Cancer Chemother Pharmacol. 2011 Aug;68(2):279-84. doi: 10.1007/s00280-010-1485-8. Epub 2010 Oct 19. Cancer Chemother Pharmacol. 2011. PMID: 20957480
Phase I/II study of FOLFIRI in Japanese patients with advanced colorectal cancer.
Yamashita K, Nagashima F, Fujita K, Yamamoto W, Endo H, Miya T, Narabayashi M, Kawara K, Akiyama Y, Ando Y, Ando M, Sasaki Y. Yamashita K, et al. Among authors: miya t. Jpn J Clin Oncol. 2011 Feb;41(2):204-9. doi: 10.1093/jjco/hyq197. Epub 2010 Oct 21. Jpn J Clin Oncol. 2011. PMID: 20965940 Clinical Trial.
Pharmacokinetics of 5-fluorouracil in elderly Japanese patients with cancer treated with S-1 (a combination of tegafur and dihydropyrimidine dehydrogenase inhibitor 5-chloro-2,4-dihydroxypyridine).
Fujita K, Nakayama H, Ichikawa W, Yamamoto W, Endo H, Nagashima F, Tanaka R, Miya T, Sunakawa Y, Yamashita K, Mizuno K, Ishida H, Araki K, Narabayashi M, Miwa K, Ando Y, Akiyama Y, Kawara K, Hirose T, Sasaki Y. Fujita K, et al. Among authors: miya t. Drug Metab Dispos. 2009 Jul;37(7):1375-7. doi: 10.1124/dmd.109.027052. Epub 2009 Apr 23. Drug Metab Dispos. 2009. PMID: 19389859
211 results