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NADPH oxidase-mediated reactive oxygen species production activates hypoxia-inducible factor-1 (HIF-1) via the ERK pathway after hyperthermia treatment.
Moon EJ, Sonveaux P, Porporato PE, Danhier P, Gallez B, Batinic-Haberle I, Nien YC, Schroeder T, Dewhirst MW. Moon EJ, et al. Among authors: gallez b. Proc Natl Acad Sci U S A. 2010 Nov 23;107(47):20477-82. doi: 10.1073/pnas.1006646107. Epub 2010 Nov 8. Proc Natl Acad Sci U S A. 2010. PMID: 21059928 Free PMC article.
Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice.
Sonveaux P, Végran F, Schroeder T, Wergin MC, Verrax J, Rabbani ZN, De Saedeleer CJ, Kennedy KM, Diepart C, Jordan BF, Kelley MJ, Gallez B, Wahl ML, Feron O, Dewhirst MW. Sonveaux P, et al. Among authors: gallez b. J Clin Invest. 2008 Dec;118(12):3930-42. doi: 10.1172/JCI36843. Epub 2008 Nov 20. J Clin Invest. 2008. PMID: 19033663 Free PMC article.
Nitric oxide delivery to cancer: why and how?
Sonveaux P, Jordan BF, Gallez B, Feron O. Sonveaux P, et al. Among authors: gallez b. Eur J Cancer. 2009 May;45(8):1352-69. doi: 10.1016/j.ejca.2008.12.018. Epub 2009 Jan 17. Eur J Cancer. 2009. PMID: 19153039 Review.
Activated macrophages as a novel determinant of tumor cell radioresponse: the role of nitric oxide-mediated inhibition of cellular respiration and oxygen sparing.
Jiang H, De Ridder M, Verovski VN, Sonveaux P, Jordan BF, Law K, Monsaert C, Van den Berge DL, Verellen D, Feron O, Gallez B, Storme GA. Jiang H, et al. Among authors: gallez b. Int J Radiat Oncol Biol Phys. 2010 Apr;76(5):1520-7. doi: 10.1016/j.ijrobp.2009.10.047. Int J Radiat Oncol Biol Phys. 2010. PMID: 20338478
285 results