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Viral entry inhibitors targeted to the membrane site of action.
Porotto M, Yokoyama CC, Palermo LM, Mungall B, Aljofan M, Cortese R, Pessi A, Moscona A. Porotto M, et al. Among authors: cortese r. J Virol. 2010 Jul;84(13):6760-8. doi: 10.1128/JVI.00135-10. Epub 2010 Mar 31. J Virol. 2010. PMID: 20357085 Free PMC article.
Universal influenza B vaccine based on the maturational cleavage site of the hemagglutinin precursor.
Bianchi E, Liang X, Ingallinella P, Finotto M, Chastain MA, Fan J, Fu TM, Song HC, Horton MS, Freed DC, Manger W, Wen E, Shi L, Ionescu R, Price C, Wenger M, Emini EA, Cortese R, Ciliberto G, Shiver JW, Pessi A. Bianchi E, et al. Among authors: cortese r. J Virol. 2005 Jun;79(12):7380-8. doi: 10.1128/JVI.79.12.7380-7388.2005. J Virol. 2005. PMID: 15919893 Free PMC article.
Dramatic potentiation of the antiviral activity of HIV antibodies by cholesterol conjugation.
Lacek K, Urbanowicz RA, Troise F, De Lorenzo C, Severino V, Di Maro A, Tarr AW, Ferrara F, Ploss A, Temperton N, Ball JK, Nicosia A, Cortese R, Pessi A. Lacek K, et al. Among authors: cortese r. J Biol Chem. 2014 Dec 12;289(50):35015-28. doi: 10.1074/jbc.M114.591826. Epub 2014 Oct 23. J Biol Chem. 2014. PMID: 25342747 Free PMC article.
A first-in-human study of the novel HIV-fusion inhibitor C34-PEG4-Chol.
Quinn K, Traboni C, Penchala SD, Bouliotis G, Doyle N, Libri V, Khoo S, Ashby D, Weber J, Nicosia A, Cortese R, Pessi A, Winston A. Quinn K, et al. Among authors: cortese r. Sci Rep. 2017 Aug 25;7(1):9447. doi: 10.1038/s41598-017-09230-0. Sci Rep. 2017. PMID: 28842581 Free PMC article. Clinical Trial.
Product inhibition of the hepatitis C virus NS3 protease.
Steinkühler C, Biasiol G, Brunetti M, Urbani A, Koch U, Cortese R, Pessi A, De Francesco R. Steinkühler C, et al. Among authors: cortese r. Biochemistry. 1998 Jun 23;37(25):8899-905. doi: 10.1021/bi980313v. Biochemistry. 1998. PMID: 9636031
398 results