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Page 1
BRCA2 acts as a RAD51 loader to facilitate telomere replication and capping.
Badie S, Escandell JM, Bouwman P, Carlos AR, Thanasoula M, Gallardo MM, Suram A, Jaco I, Benitez J, Herbig U, Blasco MA, Jonkers J, Tarsounas M. Badie S, et al. Among authors: escandell jm. Nat Struct Mol Biol. 2010 Dec;17(12):1461-9. doi: 10.1038/nsmb.1943. Epub 2010 Nov 14. Nat Struct Mol Biol. 2010. PMID: 21076401 Free PMC article.
p53 prevents entry into mitosis with uncapped telomeres.
Thanasoula M, Escandell JM, Martinez P, Badie S, Muñoz P, Blasco MA, Tarsounas M. Thanasoula M, et al. Among authors: escandell jm. Curr Biol. 2010 Mar 23;20(6):521-6. doi: 10.1016/j.cub.2010.01.046. Epub 2010 Mar 11. Curr Biol. 2010. PMID: 20226664 Free PMC article.
53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers.
Bouwman P, Aly A, Escandell JM, Pieterse M, Bartkova J, van der Gulden H, Hiddingh S, Thanasoula M, Kulkarni A, Yang Q, Haffty BG, Tommiska J, Blomqvist C, Drapkin R, Adams DJ, Nevanlinna H, Bartek J, Tarsounas M, Ganesan S, Jonkers J. Bouwman P, et al. Among authors: escandell jm. Nat Struct Mol Biol. 2010 Jun;17(6):688-95. doi: 10.1038/nsmb.1831. Epub 2010 May 9. Nat Struct Mol Biol. 2010. PMID: 20453858 Free PMC article.
Ssu72 phosphatase is a conserved telomere replication terminator.
Escandell JM, Carvalho ES, Gallo-Fernandez M, Reis CC, Matmati S, Luís IM, Abreu IA, Coulon S, Ferreira MG. Escandell JM, et al. EMBO J. 2019 Apr 1;38(7):e100476. doi: 10.15252/embj.2018100476. Epub 2019 Feb 21. EMBO J. 2019. PMID: 30796050 Free PMC article.
21 results