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AKR1B7 is induced by the farnesoid X receptor and metabolizes bile acids.
Schmidt DR, Schmidt S, Holmstrom SR, Makishima M, Yu RT, Cummins CL, Mangelsdorf DJ, Kliewer SA. Schmidt DR, et al. Among authors: mangelsdorf dj. J Biol Chem. 2011 Jan 28;286(4):2425-32. doi: 10.1074/jbc.M110.181230. Epub 2010 Nov 16. J Biol Chem. 2011. PMID: 21081494 Free PMC article.
Regulation of antibacterial defense in the small intestine by the nuclear bile acid receptor.
Inagaki T, Moschetta A, Lee YK, Peng L, Zhao G, Downes M, Yu RT, Shelton JM, Richardson JA, Repa JJ, Mangelsdorf DJ, Kliewer SA. Inagaki T, et al. Among authors: mangelsdorf dj. Proc Natl Acad Sci U S A. 2006 Mar 7;103(10):3920-5. doi: 10.1073/pnas.0509592103. Epub 2006 Feb 10. Proc Natl Acad Sci U S A. 2006. PMID: 16473946 Free PMC article.
Regulation of bile acid synthesis by fat-soluble vitamins A and D.
Schmidt DR, Holmstrom SR, Fon Tacer K, Bookout AL, Kliewer SA, Mangelsdorf DJ. Schmidt DR, et al. Among authors: mangelsdorf dj. J Biol Chem. 2010 May 7;285(19):14486-94. doi: 10.1074/jbc.M110.116004. Epub 2010 Mar 16. J Biol Chem. 2010. PMID: 20233723 Free PMC article.
Bile Acids as Hormones: The FXR-FGF15/19 Pathway.
Kliewer SA, Mangelsdorf DJ. Kliewer SA, et al. Among authors: mangelsdorf dj. Dig Dis. 2015;33(3):327-31. doi: 10.1159/000371670. Epub 2015 May 27. Dig Dis. 2015. PMID: 26045265 Free PMC article. Review.
Identification of a hormonal basis for gallbladder filling.
Choi M, Moschetta A, Bookout AL, Peng L, Umetani M, Holmstrom SR, Suino-Powell K, Xu HE, Richardson JA, Gerard RD, Mangelsdorf DJ, Kliewer SA. Choi M, et al. Among authors: mangelsdorf dj. Nat Med. 2006 Nov;12(11):1253-5. doi: 10.1038/nm1501. Epub 2006 Oct 29. Nat Med. 2006. PMID: 17072310
221 results