Nuhant P - Search Results

1

Identification of SR3335 (ML-176): a synthetic RORα selective inverse agonist.

Kumar N, Kojetin DJ, Solt LA, Kumar KG, Nuhant P, Duckett DR, Cameron MD, Butler AA, Roush WR, Griffin PR, Burris TP. Kumar N, et al. Among authors: nuhant p. ACS Chem Biol. 2011 Mar 18;6(3):218-22. doi: 10.1021/cb1002762. Epub 2010 Dec 6. ACS Chem Biol. 2011. PMID: 21090593 Free PMC article.

2

Identification of SR1078, a synthetic agonist for the orphan nuclear receptors RORα and RORγ.

Wang Y, Kumar N, Nuhant P, Cameron MD, Istrate MA, Roush WR, Griffin PR, Burris TP. Wang Y, et al. Among authors: nuhant p. ACS Chem Biol. 2010 Nov 19;5(11):1029-34. doi: 10.1021/cb100223d. ACS Chem Biol. 2010. PMID: 20735016 Free PMC article.

3

Suppression of TH17 differentiation and autoimmunity by a synthetic ROR ligand.

Solt LA, Kumar N, Nuhant P, Wang Y, Lauer JL, Liu J, Istrate MA, Kamenecka TM, Roush WR, Vidović D, Schürer SC, Xu J, Wagoner G, Drew PD, Griffin PR, Burris TP. Solt LA, et al. Among authors: nuhant p. Nature. 2011 Apr 28;472(7344):491-4. doi: 10.1038/nature10075. Epub 2011 Apr 17. Nature. 2011. PMID: 21499262 Free PMC article.

4

Enantio- and diastereoselective synthesis of N-acetyl dihydrotetrafibricin methyl ester.

Nuhant P, Roush WR. Nuhant P, et al. J Am Chem Soc. 2013 Apr 10;135(14):5340-3. doi: 10.1021/ja401918r. Epub 2013 Mar 26. J Am Chem Soc. 2013. PMID: 23530855 Free PMC article.

5

Discovery and Optimization of a Series of Sulfonamide Inverse Agonists for the Retinoic Acid Receptor-Related Orphan Receptor-α.

Doebelin C, He Y, Campbell S, Nuhant P, Kumar N, Koenig M, Garcia-Ordonez R, Chang MR, Roush WR, Lin L, Kahn S, Cameron MD, Griffin PR, Solt LA, Kamenecka TM. Doebelin C, et al. Among authors: nuhant p. Med Chem. 2019;15(6):676-684. doi: 10.2174/1573406415666190222124745. Med Chem. 2019. PMID: 30799793

6

Enantio- and diastereoselective synthesis of (E)-1,5-syn-diols: application to the synthesis of the C(23)-C(40) fragment of tetrafibricin.

Kister J, Nuhant P, Lira R, Sorg A, Roush WR. Kister J, et al. Among authors: nuhant p. Org Lett. 2011 Apr 1;13(7):1868-71. doi: 10.1021/ol2003836. Epub 2011 Mar 4. Org Lett. 2011. PMID: 21375316 Free PMC article.

7

Diisopinocampheylborane-mediated reductive aldol reactions: highly enantio- and diastereoselective synthesis of syn aldols from N-acryloylmorpholine.

Nuhant P, Allais C, Roush WR. Nuhant P, et al. Angew Chem Int Ed Engl. 2013 Aug 12;52(33):8703-7. doi: 10.1002/anie.201302535. Epub 2013 Jul 1. Angew Chem Int Ed Engl. 2013. PMID: 23818095 Free PMC article.

8

Antiproliferation activity of a small molecule repressor of liver receptor homolog 1.

Corzo CA, Mari Y, Chang MR, Khan T, Kuruvilla D, Nuhant P, Kumar N, West GM, Duckett DR, Roush WR, Griffin PR. Corzo CA, et al. Among authors: nuhant p. Mol Pharmacol. 2015 Feb;87(2):296-304. doi: 10.1124/mol.114.095554. Epub 2014 Dec 3. Mol Pharmacol. 2015. PMID: 25473120 Free PMC article.

9

(Diisopinocampheyl)borane-mediated reductive aldol reactions of acrylate esters: enantioselective synthesis of anti-aldols.

Allais C, Nuhant P, Roush WR. Allais C, et al. Among authors: nuhant p. Org Lett. 2013 Aug 2;15(15):3922-5. doi: 10.1021/ol401679g. Epub 2013 Jul 25. Org Lett. 2013. PMID: 23885946 Free PMC article.

10

Generation of stereochemically defined tetrasubstituted enolborinates by 1,4-hydroboration of α,β-unsaturated morpholine carboxamides with (diisopinocampheyl)borane.

Allais C, Tsai AS, Nuhant P, Roush WR. Allais C, et al. Among authors: nuhant p. Angew Chem Int Ed Engl. 2013 Dec 2;52(49):12888-12891. doi: 10.1002/anie.201307302. Epub 2013 Oct 15. Angew Chem Int Ed Engl. 2013. PMID: 24281884 Free PMC article.

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